HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: H90B2 (Q58FF8)
Putative heat shock protein HSP 90-beta 2 (Heat shock protein 90-beta b) (Heat shock protein 90Bb)
Gene: HSP90AB2P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0034605 - cellular response to heat
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 381
+	Hs
		496215 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		ENPL_HUMAN (185-381): 1.31e-65: 224: 34.98
+	Hs
		496938 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TRAP1_HUMAN (135-380): 3.01e-42: 158: 20.45
+	Hs
		497143 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		H90B4_HUMAN (109-247): 1.76e-32: 129: 75.54
+	Hs
		437833 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41
+	Hs
		431463 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Rn
		581936 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HS90B_RAT (109-251): 9.78e-33: 131: 86.71
+	Rn
		94158 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HS90B_RAT (109-251): 9.78e-33: 131: 86.71
+	Rn
		581980 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HS90A_RAT (87-251): 1.57e-26: 113: 59.41
+	Rn
		94203 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HS90A_RAT (87-251): 1.57e-26: 113: 59.41
+	Hs
		431504 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		HS90A_HUMAN (87-251): 2.97e-26: 112: 61.54
+	Hs
		438364 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		HS90B_HUMAN (109-251): 8.66e-32: 128: 87.41