Protein: MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)

Gene: MCCB, Mccc2
Organism: Mus musculus
Interactions: 17
UniProt ID: Q3ULD5

Gene Ontology (top 5):
GO:0004485 - methylcrotonoyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006552 - L-leucine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1190518

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

3

15

High-throughput

0.827

High

1190519

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

1

High-throughput

0.489

High

1190520

BRSK2
Serine/threonine-protein kinase BRSK2

1

5

High-throughput

0.479

High

1190522

TAOK2
Serine/threonine-protein kinase TAO2

1

8

High-throughput

0.479

High

1190524

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

1

High-throughput

0.479

High

46537

SIM43
Small integral membrane protein 43

1

1

High-throughput

0.437

High

398414

CFAD
Complement factor D

1

2

High-throughput

0.437

High

1190525

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.437

High

1190526

HSPB2
Heat shock protein beta-2

1

2

High-throughput

0.437

High

1021685

THIOM
Thioredoxin, mitochondrial

1

0

High-throughput

0.426

High

569630

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.407

High

651525

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.407

High

1190521

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.407

High

1190523

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.249

Low

267100

MYPC3
Myosin-binding protein C, cardiac-type

1

0

High-throughput

0.232

Low

905846

CAV3
Caveolin-3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025