Interactor 1: MCCB (Q3ULD5)
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)
Gene: Mccc2

Interactor 2: MCCB (Q3ULD5)
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCase subunit beta) (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta)
Gene: Mccc2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Carboxyl_trans~Carboxyl_trans
Common GO terms GO:0004485 - methylcrotonoyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006552 - L-leucine catabolic process
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 563
Mm

1 563
+ Hs
+ Hs
+ Pa
+ Hs
+ Mm
+ Mt
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Ss
+ Ss
+ Hp

Service provided by Combinatics, Japan

Last updated: 11Aug2025