HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 712
+	Hs
		497686 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TAB2_HUMAN (1-711): 6.6e-48: 182: 30.53
+	Hs
		496597 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SMCA2_HUMAN (176-599): 1.02e-36: 150: 13.59
+	Hs
		203203 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SYNJ1_HUMAN (252-685): 6.15e-21: 100: 11.19
+	Hs
		496630 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SC24C_HUMAN (210-493): 5.8e-12: 71.3: 13.44
+	Rn
		582007 TAU_RAT (1-758): 4.86e-75: 260: 71.47		SYNJ1_RAT (245-683): 3.65e-23: 107: 10.82
+	Rn
		94231 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		SYNJ1_RAT (245-683): 3.65e-23: 107: 10.82
+	Mm
		88453 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		D3Z656_MOUSE (245-683): 1.04e-27: 122: 12.14
+	Hs
		302246 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		SC31A_HUMAN (220-598): 4.01e-10: 65.5: 13.19
+	Hs
		497357 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		TITIN_HUMAN (134-417): 2.57e-09: 63.2: 9.72
+	Hs
		1056876 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		MICA3_HUMAN (61-685): 7.87e-31: 132: 9.58
+	Mm
		1207212 NCOA6_MOUSE (23-739): 1.31e-24: 112: 9.76		KMT2C_MOUSE (35-686): 1.39e-23: 109: 10.39
+	Hs
		554259 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		MUC1_HUMAN (54-680): 4.91e-23: 107: 9.24
+	Hs
		1056937 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		CHAP1_HUMAN (63-511): 1.2e-19: 96: 13.16
+	Dm
		113976 M9PB30_DROME (69-755): 2.38e-24: 112: 8.39		M9PB30_DROME (78-686): 9.62e-15: 81: 9.63
+	Hs
		123781 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		SPT5H_HUMAN (58-209): 8.32e-09: 61.3: 13.64
+	Mm
		1351630 PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66		PCLO_MOUSE (182-697): 3.56e-11: 69: 10.47
+	Hs
		1336185 MAGE1_HUMAN (222-587): 4.83e-09: 61.9: 16.22		MAGE1_HUMAN (139-488): 6.26e-10: 64.7: 15.43