HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: BMP4 (P12644)
Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
Gene: BMP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 408
+	Hs
		351233 HSP7C_HUMAN (26-637): 0: 916: 66.02		TGFB1_HUMAN (47-407): 5.81e-81: 255: 21.45
+	Hs
		351231 BIP_HUMAN (19-654): 0: 914: 100.00		TGFB1_HUMAN (47-407): 5.81e-81: 255: 21.45
+	Hs
		312843 BIP_HUMAN (19-654): 0: 914: 100.00		GDF11_HUMAN (46-407): 1.52e-71: 232: 21.60
+	Hs
		501889 BIP_HUMAN (19-654): 0: 914: 100.00		INHBE_HUMAN (24-407): 1.44e-67: 219: 24.17