HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36042349
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 654 Hs			1 340
+	Hs
		503848 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		564054 HSP76_HUMAN (25-635): 0: 915: 62.54		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		483785 HS71B_HUMAN (26-635): 0: 911: 64.11		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		871525 HSP72_HUMAN (25-636): 0: 905: 64.51		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		503846 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		501942 BIP_HUMAN (19-654): 0: 914: 100.00		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		920985 Q53FC7_HUMAN (25-635): 0: 912: 62.05		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		871524 HSP72_HUMAN (25-636): 0: 905: 64.51		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		504344 HSP7C_HUMAN (26-637): 0: 916: 66.02		WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39
+	Hs
		714020 HS71L_HUMAN (24-647): 0: 922: 63.16		POC1A_HUMAN (3-125): 4.59e-25: 106: 16.92
+	Hs
		504412 HSP7C_HUMAN (26-637): 0: 916: 66.02		POC1A_HUMAN (3-125): 4.59e-25: 106: 16.92
+	Hs
		564125 HSP76_HUMAN (25-635): 0: 915: 62.54		POC1A_HUMAN (3-125): 4.59e-25: 106: 16.92
+	Hs
		503614 HSP7C_HUMAN (26-637): 0: 916: 66.02		LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89
+	Hs
		503817 HSP7C_HUMAN (26-637): 0: 916: 66.02		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92
+	Hs
		501913 BIP_HUMAN (19-654): 0: 914: 100.00		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92
+	Sc
		560644 BIP_YEAST (22-638): 0: 798: 68.82		TAF5_YEAST (180-340): 1.96e-11: 67: 23.29