HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: CHD1 (P32657)
Chromo domain-containing protein 1 (EC 3.6.4.-) (ATP-dependent helicase CHD1)
Gene: CHD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	29019976, 37968396, 21179020
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 1468
+	Sc
		355836 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		CHD1_YEAST (1-1468): 0: 1114: 100.00
+	Hs
		1307128 H2B1M_HUMAN (7-128): 9.18e-47: 148: 69.36		CHD8_HUMAN (2-1377): 0: 934: 26.15
+	Hs
		1087418 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		CHD8_HUMAN (2-1377): 0: 934: 26.15
+	Hs
		707755 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		CHD8_HUMAN (2-1377): 0: 934: 26.15
+	Hs
		707647 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		CHD9_HUMAN (20-1378): 0: 921: 26.06
+	Hs
		151482 H2BFS_HUMAN (7-128): 4.79e-46: 147: 68.55		CHD2_HUMAN (5-1468): 0: 876: 31.11
+	Hs
		658684 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SMCA1_HUMAN (253-1259): 0: 778: 27.19
+	Hs
		229415 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SMCA5_HUMAN (245-1274): 0: 777: 26.33
+	Hs
		229458 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		SMCA5_HUMAN (245-1274): 0: 777: 26.33
+	Hs
		229321 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		SMCA5_HUMAN (245-1274): 0: 777: 26.33
+	Hs
		846990 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SMCA4_HUMAN (3-1106): 0: 755: 23.19
+	Sc
		356040 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		ISW2_YEAST (364-933): 1.41e-126: 424: 42.98
+	Hs
		1087449 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		CHD7_HUMAN (923-1410): 1.58e-18: 94.7: 11.27
+	Hs
		707773 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		CHD7_HUMAN (923-1410): 1.58e-18: 94.7: 11.27
+	Hs
		1018625 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		CHD3_HUMAN (959-1364): 1.33e-13: 78.5: 9.57
+	Hs
		241517 H2B1K_HUMAN (7-128): 1.06e-45: 146: 70.16		CHD3_HUMAN (959-1364): 1.33e-13: 78.5: 9.57
+	Hs
		707612 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		CHD3_HUMAN (959-1364): 1.33e-13: 78.5: 9.57
+	Hs
		1059648 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		CHD4_HUMAN (959-1353): 6.6e-11: 69.7: 12.19
+	Hs
		1059777 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		CHD4_HUMAN (959-1353): 6.6e-11: 69.7: 12.19
+	Hs
		707635 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		CHD4_HUMAN (959-1353): 6.6e-11: 69.7: 12.19