HitPredict

Interactor 1: H2A1 (P0C0S8)
Histone H2A type 1 (H2A.1) (Histone H2A/ptl)
Gene: H2AC11

Interactor 2: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34349018, 35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Linker_histone
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 213
+	Hs
		595678 H2A1D_HUMAN (1-130): 1.15e-66: 199: 99.23		H13_HUMAN (1-181): 4.8e-25: 99.5: 82.42
+	Hs
		595811 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		H13_HUMAN (1-181): 4.8e-25: 99.5: 82.42
+	Hs
		595836 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		H13_HUMAN (1-181): 4.8e-25: 99.5: 82.42
+	Hs
		633997 H2A1D_HUMAN (1-130): 1.15e-66: 199: 99.23		H1T_HUMAN (1-183): 5.27e-24: 96.4: 53.40
+	Hs
		649350 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		H1T_HUMAN (1-183): 5.27e-24: 96.4: 53.40
+	Hs
		649384 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		H1T_HUMAN (1-183): 5.27e-24: 96.4: 53.40
+	Hs
		595931 H2A1D_HUMAN (1-130): 1.15e-66: 199: 99.23		H12_HUMAN (1-173): 1.54e-22: 92.6: 100.00
+	Hs
		596191 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		H12_HUMAN (1-173): 1.54e-22: 92.6: 100.00
+	Hs
		596282 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		H12_HUMAN (1-173): 1.54e-22: 92.6: 100.00
+	Hs
		418802 H2A1B_HUMAN (1-130): 1.37e-66: 199: 98.46		H14_HUMAN (1-172): 4.98e-18: 80.6: 88.37
+	Hs
		521534 H2A1D_HUMAN (1-130): 1.15e-66: 199: 99.23		H14_HUMAN (1-172): 4.98e-18: 80.6: 88.37
+	Hs
		521776 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		H14_HUMAN (1-172): 4.98e-18: 80.6: 88.37
+	Hs
		521842 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		H14_HUMAN (1-172): 4.98e-18: 80.6: 88.37
+	Hs
		418817 H2A1B_HUMAN (1-130): 1.37e-66: 199: 98.46		H15_HUMAN (1-157): 2.06e-15: 74.1: 76.25
+	Hs
		595312 H2A1D_HUMAN (1-130): 1.15e-66: 199: 99.23		H15_HUMAN (1-157): 2.06e-15: 74.1: 76.25
+	Hs
		595488 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		H15_HUMAN (1-157): 2.06e-15: 74.1: 76.25
+	Hs
		595543 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		H15_HUMAN (1-157): 2.06e-15: 74.1: 76.25
+	Hs
		1037233 H2A3_HUMAN (1-130): 1.16e-66: 199: 97.69		H11_HUMAN (38-182): 2.88e-15: 73.3: 62.07
+	Hs
		1037302 H2A1C_HUMAN (1-130): 1.03e-66: 199: 98.46		H11_HUMAN (38-182): 2.88e-15: 73.3: 62.07
+	Hs
		634021 H2A1D_HUMAN (1-130): 1.15e-66: 199: 99.23		H11_HUMAN (38-182): 2.88e-15: 73.3: 62.07