Interactor 1: CAN3 (P20807)
Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)
Gene: CAPN3

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.883

The method score is based on:

Property Details
Experiments 9642272, 23414517, 8537379, 20860623
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_6~Pkinase, EF-hand_8~Pkinase
Common GO terms GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0008307 - structural constituent of muscle
GO:0030018 - Z disc
GO:0045214 - sarcomere organization
and 2 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 821
Hs

1 34350
+ Hs
+ Mm
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+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024