Interactor 1: DEGP (P0C0V0)
Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do)
Gene: DEGP
Interactor 2: DEGP (P0C0V0)
Periplasmic serine endoprotease DegP (EC 3.4.21.107) (Heat shock protein DegP) (Protease Do)
Gene: DEGP
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18496527, 18697939, 20581825, 20581826, 21893291, 24373769, 21458668 |
| Identification Methods | x-ray crystallography, molecular sieving, 3D electron microscopy, dynamic light scattering, cross-linking study, cosedimentation in solution, mass spectrometry studies of complexes, protease assay |
| Interaction Type | direct interaction, protein cleavage, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDZ~PDZ, PDZ~Trypsin_2, Trypsin_2~Trypsin_2 |
| Common GO terms | GO:0004252 - serine-type endopeptidase activity GO:0005886 - plasma membrane GO:0006457 - protein folding GO:0006508 - proteolysis GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins and 7 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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| + | Ec |   |
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| + | Hp | |
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| + | Hp | |
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| + | Ss | |
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| + | At | |
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| + | Hs | |
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| + | Hs | |
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| + | Hs | |
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| + | Hs | |
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| + | Hs | |
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| + | Hs | |
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| + | Ec | |
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| + | Hs |  |
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| + | At | |
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| + | Sp | |
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| + | Sp |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
