Protein: AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1)

Gene: AREL1
Organism: Homo sapiens
Interactions: 29
UniProt ID: O15033

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

165282

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.919

High

165285

UB2L3
Ubiquitin-conjugating enzyme E2 L3

4

20

Small-scale

0.888

High

165278

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

20

Small-scale

0.845

High

165272

AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1

2

15

Small-scale

0.778

High

165283

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

165284

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

Small-scale

0.647

High

165290

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

6

High-throughput

0.628

High

165280

CRKL
Crk-like protein

2

5

High-throughput

0.594

High

165287

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

2

1

High-throughput

0.574

High

165296

PCDGG
Protocadherin gamma-B4

2

3

High-throughput

0.574

High

165299

PCDG5
Protocadherin gamma-A5

2

3

High-throughput

0.574

High

165273

SOCS1
Suppressor of cytokine signaling 1

1

6

Small-scale

0.561

High

165274

SEPT4
Septin-4

1

2

Small-scale

0.561

High

165275

HTRA2
Serine protease HTRA2, mitochondrial

1

1

Small-scale

0.561

High

165288

PIAS4
E3 SUMO-protein ligase PIAS4

1

4

Small-scale

0.561

High

165293

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

Small-scale

0.537

High

165279

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

2

High-throughput

0.489

High

165291

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

1

High-throughput

0.489

High

165297

PCDGL
Protocadherin gamma-C4

1

3

High-throughput

0.489

High

165298

PCDGE
Protocadherin gamma-B2

1

3

High-throughput

0.489

High

165276

HS90A
Heat shock protein HSP 90-alpha

1

14

High-throughput

0.479

High

165277

HS90B
Heat shock protein HSP 90-beta

1

14

High-throughput

0.479

High

165281

GSK3B
Glycogen synthase kinase-3 beta

1

4

Small-scale

0.479

High

165294

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

165292

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

165286

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

165289

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

165295

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024