HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: MK15 (Q8TD08)
Mitogen-activated protein kinase 15 (MAP kinase 15) (MAPK 15) (EC 2.7.11.24) (Extracellular signal-regulated kinase 7) (ERK-7) (Extracellular signal-regulated kinase 8) (ERK-8)
Gene: MAPK15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005776 - autophagosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 544
+	Hs
		503460 HSP7C_HUMAN (1-646): 0: 967: 100.00		CDK2_HUMAN (10-315): 6.34e-141: 410: 38.31
+	Hs
		504142 HSP7C_HUMAN (1-646): 0: 967: 100.00		MK14_HUMAN (8-355): 1.49e-135: 399: 38.92
+	Hs
		503902 HSP7C_HUMAN (1-646): 0: 967: 100.00		CDK3_HUMAN (10-316): 8.82e-136: 397: 38.19
+	Hs
		713942 HS71L_HUMAN (2-646): 0: 966: 82.48		CDK3_HUMAN (10-316): 8.82e-136: 397: 38.19
+	Hs
		503480 HSP7C_HUMAN (1-646): 0: 967: 100.00		MK03_HUMAN (12-313): 8.66e-78: 251: 45.25
+	Rn
		600359 HS71L_RAT (2-646): 0: 967: 83.26		MK03_RAT (12-313): 1.32e-77: 251: 45.25
+	Rn
		600371 HSP7C_RAT (1-646): 0: 967: 99.85		MK03_RAT (12-313): 1.32e-77: 251: 45.25
+	Rn
		483814 HS71B_RAT (1-646): 0: 958: 84.06		MK03_RAT (12-313): 1.32e-77: 251: 45.25
+	Hs
		564010 HSP76_HUMAN (6-646): 0: 955: 77.54		MK03_HUMAN (12-313): 8.66e-78: 251: 45.25
+	Rn
		538777 HSP72_RAT (2-612): 0: 936: 87.77		MK03_RAT (12-313): 1.32e-77: 251: 45.25