Interactor 1: PAN2 (P0C581)
PAN2-PAN3 deadenylation complex catalytic subunit pan2 (EC 3.1.13.4) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: par-1
Interactor 2: PAN3 (Q7SDP4)
PAN2-PAN3 deadenylation complex subunit pan3 (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 3) (PAN deadenylation complex subunit 3)
Gene: par-2
Species: Neurospora crassa OR74A
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24880343 |
| Identification Methods | pull down, x-ray crystallography, static light scattering, molecular sieving |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PAN2_N~Pan3_PK, Pan3_PK~UCH_1 |
| Common GO terms | GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening GO:0000932 - P-body GO:0006397 - mRNA processing GO:0031251 - PAN complex |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
