HitPredict

Interactor 1: ODB2 (P11182)
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (52 kDa mitochondrial autoantigen of primary biliary cirrhosis) (Branched chain 2-oxo-acid dehydrogenase complex component E2) (BCOADC-E2) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (BCKDH-E2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)
Gene: DBT

Interactor 2: RUSD3 (Q6P087)
Mitochondrial mRNA pseudouridine synthase RPUSD3 (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 3)
Gene: RPUSD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 351
+	Hs
		506022 ODB2_HUMAN (1-482): 0: 635: 100.00		RUSD4_HUMAN (42-350): 5.75e-82: 255: 25.60
+	Hs
		739159 ODO2_HUMAN (52-481): 3.5e-140: 412: 24.54		RUSD3_HUMAN (1-351): 5.56e-128: 372: 100.00
+	Hs
		739223 ODO2_HUMAN (52-481): 3.5e-140: 412: 24.54		RUSD4_HUMAN (42-350): 5.75e-82: 255: 25.60
+	Hs
		489764 ODP2_HUMAN (40-137): 9.92e-23: 103: 21.21		RUSD3_HUMAN (1-351): 5.56e-128: 372: 100.00
+	Ec
		420922 ODP2_ECOLI (64-473): 5.99e-45: 168: 29.35		RLUC_ECOLI (68-347): 1.1e-67: 217: 20.64
+	Hs
		489789 ODP2_HUMAN (40-137): 9.92e-23: 103: 21.21		RUSD4_HUMAN (42-350): 5.75e-82: 255: 25.60