Interactor 1: ERG (P11308)
Transcriptional regulator ERG (Transforming protein ERG)
Gene: ERG

Interactor 2: NDF2 (Q15784)
Neurogenic differentiation factor 2 (NeuroD2) (Class A basic helix-loop-helix protein 1) (bHLHa1) (NeuroD-related factor) (NDRF)
Gene: NEUROD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 479
Hs

1 382
+ Mm
+ Mm
+ Mm
+ Dm
+ Dm
+ Mm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024