Protein: ATG18
Autophagy-related protein 18 (Cytoplasm to vacuole targeting protein 18) (Needed for premeiotic replication protein 1) (Swollen vacuole phenotype protein 1)

Gene: ATG18
Organism: Saccharomyces cerevisiae S288C
Interactions: 73
UniProt ID: P43601

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000329 - fungal-type vacuole membrane
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0000425 - pexophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850419

ATG2
Autophagy-related protein 2

18

9

Small-scale

0.765

High

850409

ATG18
Autophagy-related protein 18

1

16

Small-scale

0.710

High

850431

ATG9
Autophagy-related protein 9

5

3

Small-scale

0.710

High

850424

ATG16
Autophagy protein 16

1

1

Small-scale

0.647

High

677719

VAC17
vacuole-related protein 17

3

0

Small-scale

0.646

High

850428

VAC14
Vacuole morphology and inheritance protein 14

3

0

Small-scale

0.643

High

757382

VPS35
Vacuolar protein sorting-associated protein 35

3

0

Small-scale

0.640

High

850412

SA155
SIT4-associating protein SAP155

3

0

Small-scale

0.634

High

822479

PEP8
Carboxypeptidase Y-deficient protein 8

3

0

Small-scale

0.613

High

850422

2ABA
Protein phosphatase PP2A regulatory subunit B

2

1

Small-scale

0.611

High

850417

ATG1
Serine/threonine-protein kinase ATG1

2

3

Small-scale

0.602

High

760539

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

2

20

Small-scale

0.586

High

803508

VPS29
Vacuolar protein sorting-associated protein 29

2

0

Small-scale

0.559

High

633480

PP11
Serine/threonine-protein phosphatase PP1-1

2

3

Small-scale

0.558

High

526995

HSP72
Heat shock protein SSA2

2

14

High-throughput

0.552

High

819075

SSB2
Ribosome-associated molecular chaperone SSB2

2

16

High-throughput

0.552

High

358258

ADH1
Alcohol dehydrogenase 1

2

1

High-throughput

0.537

High

850430

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.536

High

850421

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.518

High

509609

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

11

Small-scale

0.501

High

656514

KC11
Casein kinase I homolog 1

1

8

High-throughput

0.501

High

797969

ATG12
Ubiquitin-like protein ATG12

1

1

Small-scale

0.501

High

850432

ATG5
Autophagy protein 5

1

2

Small-scale

0.501

High

359492

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

4

High-throughput

0.500

High

405107

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.500

High

645749

HSP74
Heat shock protein SSA4

1

14

High-throughput

0.500

High

850410

LSB3
LAS seventeen-binding protein 3

1

4

High-throughput

0.494

High

850427

UTP13
U3 small nucleolar RNA-associated protein 13

1

17

High-throughput

0.489

High

575254

RAD4
DNA repair protein RAD4

1

0

Small-scale

0.486

High

794748

RTG3
Retrograde regulation protein 3

1

0

Small-scale

0.486

High

793166

AKL1
Serine/threonine-protein kinase AKL1

1

0

High-throughput

0.480

High

458579

SEC4
Ras-related protein SEC4

1

5

High-throughput

0.479

High

582484

SEC23
Protein transport protein SEC23

1

3

High-throughput

0.479

High

639031

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.479

High

679813

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

732165

COPG
Coatomer subunit gamma

1

3

High-throughput

0.479

High

743347

FIMB
Fimbrin

1

4

High-throughput

0.479

High

748753

YPT7
Ypt/Rab-type GTPase YPT7

1

6

High-throughput

0.479

High

835507

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase BUB1

1

3

Small-scale

0.479

High

850420

DID2
Vacuolar protein-sorting-associated protein 46

1

1

High-throughput

0.479

High

850425

GIS1
Transcriptional activator/repressor GIS1

1

4

High-throughput

0.479

High

850416

BIOA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

1

2

Small-scale

0.464

High

746444

SSO1
Protein SSO1

1

0

High-throughput

0.458

High

794785

SFT2
Protein transport protein SFT2

1

0

High-throughput

0.458

High

825965

GVP36
Protein GVP36

1

0

High-throughput

0.458

High

850429

SNX3
Sorting nexin-3

1

0

Small-scale

0.458

High

602528

PHO85
Cyclin-dependent protein kinase PHO85

1

5

High-throughput

0.457

High

748858

SWE1
Mitosis inhibitor protein kinase SWE1

1

8

High-throughput

0.457

High

850413

TOS3
Serine/threonine-protein kinase TOS3

1

1

High-throughput

0.457

High

392927

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

394672

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

435175

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.445

High

524327

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

545316

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.445

High

707434

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

835999

COPB
Coatomer subunit beta

1

2

High-throughput

0.437

High

850418

GIS2
Zinc finger protein GIS2

1

4

Small-scale

0.437

High

646442

RAD53
Serine/threonine-protein kinase RAD53

1

0

Small-scale

0.426

High

850423

UBC7
Ubiquitin-conjugating enzyme E2 7

1

9

High-throughput

0.417

High

427330

RLA0
Large ribosomal subunit protein uL10

1

6

High-throughput

0.407

High

850433

GIS3
Protein GIS3

3

0

Small-scale

0.339

High

804776

TRM5
tRNA

1

0

High-throughput

0.269

Low

805258

SBE22
Protein SBE22

1

0

Small-scale

0.265

Low

850415

HIR3
Histone transcription regulator 3

1

0

Small-scale

0.265

Low

850426

NTE1
Lysophospholipase NTE1

1

0

Small-scale

0.265

Low

470034

GAL7
Galactose-1-phosphate uridylyltransferase

1

0

High-throughput

0.261

Low

550766

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.261

Low

806695

AIM46
Altered inheritance of mitochondria protein 46, mitochondrial

1

0

High-throughput

0.261

Low

850411

PTR3
SPS-sensor component PTR3

1

0

Small-scale

0.251

Low

850414

3HAO
3-hydroxyanthranilate 3,4-dioxygenase

1

0

Small-scale

0.251

Low

812196

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

Small-scale

0.249

Low

830001

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025