Protein: WIPI1
WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (Atg18 protein homolog) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa)

Gene: WIPI1
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q5MNZ9

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000139 - Golgi membrane
GO:0000407 - phagophore assembly site
GO:0000421 - autophagosome membrane
GO:0000422 - autophagy of mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992788

RACK1
Small ribosomal subunit protein RACK1

3

19

High-throughput

0.667

High

1208397

CEP76
Centrosomal protein of 76 kDa

3

0

High-throughput

0.638

High

1208390

A16L1
Autophagy-related protein 16-1

1

17

Small-scale

0.618

High

1208404

UHRF1
E3 ubiquitin-protein ligase UHRF1

3

14

High-throughput

0.609

High

1208389

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

19

High-throughput

0.575

High

868710

LEG7
Galectin-7

1

4

High-throughput

0.536

High

1117946

PKP1
Plakophilin-1

1

6

High-throughput

0.536

High

1180273

ATG2A
Autophagy-related protein 2 homolog A

1

10

High-throughput

0.536

High

396271

ESR1
Estrogen receptor

1

20

Small-scale

0.501

High

520107

ANDR
Androgen receptor

1

20

Small-scale

0.501

High

1208403

KCD15
BTB/POZ domain-containing protein KCTD15

1

6

High-throughput

0.494

High

333669

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

1

Small-scale

0.479

High

507222

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

12

Small-scale

0.479

High

690505

KAD4
Adenylate kinase 4, mitochondrial

1

1

Small-scale

0.479

High

877340

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

2

Small-scale

0.479

High

954154

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

1208394

ATG9A
Autophagy-related protein 9A

1

3

Small-scale

0.479

High

1208400

ATG2B
Autophagy-related protein 2 homolog B

1

10

Small-scale

0.479

High

1208401

OPTN
Optineurin

1

20

Small-scale

0.479

High

1208405

ATGA1
Autophagy-related protein 101

1

1

Small-scale

0.479

High

1208406

PHAF1
Phagosome assembly factor 1

1

1

Small-scale

0.479

High

1208411

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

17

Small-scale

0.479

High

1208413

BCAS3
BCAS3 microtubule associated cell migration factor

1

8

Small-scale

0.479

High

1208416

AMFR
E3 ubiquitin-protein ligase AMFR

1

7

Small-scale

0.479

High

183348

ZN185
Zinc finger protein 185

1

0

Small-scale

0.458

High

331872

GOSR1
Golgi SNAP receptor complex member 1

1

0

Small-scale

0.458

High

724582

S10A7
Protein S100-A7

1

0

High-throughput

0.458

High

1208392

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

Small-scale

0.458

High

1208398

COG1
Conserved oligomeric Golgi complex subunit 1

1

0

Small-scale

0.458

High

1208402

EDC3
Enhancer of mRNA-decapping protein 3

1

0

Small-scale

0.458

High

1208412

OSBL5
Oxysterol-binding protein-related protein 5

1

0

Small-scale

0.458

High

1143945

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.457

High

1208414

GEMI8
Gem-associated protein 8

1

0

High-throughput

0.438

High

228824

SCO2
Protein SCO2 homolog, mitochondrial

1

1

Small-scale

0.437

High

296253

SCO1
Protein SCO1 homolog, mitochondrial

1

1

Small-scale

0.437

High

477803

RM03
Large ribosomal subunit protein uL3m

1

7

Small-scale

0.437

High

728782

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

3

Small-scale

0.437

High

842214

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

6

Small-scale

0.437

High

869174

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

1

Small-scale

0.437

High

1048544

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.437

High

1208391

ZN787
Zinc finger protein 787

1

1

Small-scale

0.437

High

1208396

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

1

1

Small-scale

0.437

High

1208409

RM13
Large ribosomal subunit protein uL13m

1

7

Small-scale

0.437

High

1208417

RT07
Small ribosomal subunit protein uS7m

1

3

Small-scale

0.437

High

1126701

BECN1
Beclin-1

1

0

High-throughput

0.426

High

1208399

DNS2B
Deoxyribonuclease-2-beta

3

0

High-throughput

0.347

High

1208393

MIGA2
Mitoguardin 2

1

0

Small-scale

0.249

Low

1208395

RM41
Large ribosomal subunit protein mL41

1

0

Small-scale

0.249

Low

1208407

HGH1
Protein HGH1 homolog

1

0

Small-scale

0.249

Low

1208408

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

Small-scale

0.249

Low

1208410

RM37
Large ribosomal subunit protein mL37

1

0

Small-scale

0.249

Low

1208415

RM35
Large ribosomal subunit protein bL35m

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025