HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: DNJA1 (P31689)
DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)
Gene: DNAJA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 397
+	Hs
		243277 FGFR1_HUMAN (1-822): 0: 861: 100.00		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		508145 FGFR1_HUMAN (1-822): 0: 861: 100.00		DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93
+	Hs
		507864 FGFR1_HUMAN (1-822): 0: 861: 100.00		DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59
+	Hs
		243293 FGFR4_HUMAN (29-808): 0: 664: 55.60		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		609471 FGFR3_HUMAN (6-821): 0: 730: 61.22		DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93
+	Hs
		608081 FGFR4_HUMAN (29-808): 0: 664: 55.60		DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93
+	Hs
		681463 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00
+	Hs
		674347 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00
+	Hs
		243425 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		384352 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		DNJA1_HUMAN (1-397): 3.98e-171: 485: 100.00
+	Hs
		243305 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		243251 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		DNJA2_HUMAN (2-395): 1.59e-148: 428: 53.55
+	Hs
		1081563 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93
+	Hs
		608166 FGFR4_HUMAN (29-808): 0: 664: 55.60		DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15
+	Hs
		636250 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59
+	Hs
		385330 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		DNJA3_HUMAN (4-387): 3.67e-116: 348: 26.93
+	Hs
		384289 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		DNJB1_HUMAN (5-347): 8.67e-117: 345: 32.59
+	Hs
		665541 EPHA8_HUMAN (3-819): 0: 603: 19.35		DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15
+	Hs
		1081636 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15
+	Hs
		674554 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		DJB11_HUMAN (7-330): 1.64e-46: 164: 36.15