HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	28190767, 18212736, 19285159, 28319114, 33182596, 34161781, 23032186
Identification Methods	pull down, affinity chromatography technology, x-ray crystallography, protein array
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 636
+	Hs
		508453 UBC_HUMAN (1-685): 0: 857: 100.00		TNIP3_HUMAN (296-538): 1.52e-59: 204: 39.20
+	Hs
		508848 UBC_HUMAN (1-685): 0: 857: 100.00		SMC3_HUMAN (278-527): 2.29e-43: 169: 25.09
+	Hs
		507464 UBC_HUMAN (1-685): 0: 857: 100.00		LAMC1_HUMAN (43-539): 7.97e-19: 93.4: 9.38
+	Hs
		508323 UBC_HUMAN (1-685): 0: 857: 100.00		RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12
+	Hs
		507477 UBC_HUMAN (1-685): 0: 857: 100.00		MYH1_HUMAN (7-434): 1.95e-14: 79.2: 12.50
+	Hs
		508032 UBC_HUMAN (1-685): 0: 857: 100.00		ITSN1_HUMAN (92-469): 4.68e-14: 78.1: 11.00
+	Hs
		507610 UBC_HUMAN (1-685): 0: 857: 100.00		MYH9_HUMAN (263-570): 8.04e-10: 64.5: 13.64
+	Sc
		477486 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		MYO1_YEAST (173-528): 5.44e-09: 61.9: 15.11
+	Hs
		987032 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00
+	Mm
		509327 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		TNIP1_MOUSE (1-636): 8.44e-64: 224: 82.28
+	Hs
		157211 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		CTRO_HUMAN (51-557): 1.7e-16: 85.8: 13.73
+	Mm
		509097 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		MYH10_MOUSE (2-508): 1.84e-19: 95.7: 10.72
+	Mm
		509331 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		ITSN1_MOUSE (27-390): 4.11e-14: 78.1: 12.43
+	Mm
		509199 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		MYH9_MOUSE (249-567): 8.39e-10: 64.5: 12.54
+	Hs
		157421 OASL_HUMAN (357-525): 2.61e-16: 84.4: 29.31		CTRO_HUMAN (51-557): 1.7e-16: 85.8: 13.73