Protein: TNIP3
TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein)

Gene: TNIP3
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q96KP6

Gene Ontology (top 5):
GO:0002756 - MyD88-independent toll-like receptor signaling pathway
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006954 - inflammatory response
GO:0031593 - polyubiquitin modification-dependent protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508453

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

Small-scale

0.713

High

1290937

TAXB1
Tax1-binding protein 1

4

18

High-throughput

0.698

High

1137945

TNIP1
TNFAIP3-interacting protein 1

3

19

High-throughput

0.675

High

1396237

LZTS2
Leucine zipper putative tumor suppressor 2

3

20

High-throughput

0.675

High

639293

TNAP3
Tumor necrosis factor alpha-induced protein 3

3

11

Small-scale

0.668

High

1396239

TRIM8
E3 ubiquitin-protein ligase TRIM8

3

12

Small-scale

0.653

High

626333

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

18

High-throughput

0.618

High

1139114

DAZP2
DAZ-associated protein 2

3

1

High-throughput

0.616

High

138748

IMA4
Importin subunit alpha-4

2

1

High-throughput

0.606

High

1185306

F161A
Protein FAM161A

2

2

High-throughput

0.606

High

1331084

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

3

High-throughput

0.606

High

1396236

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

2

High-throughput

0.606

High

1230203

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.582

High

877607

CCN3
CCN family member 3

2

0

High-throughput

0.580

High

1392844

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1396241

PLS3
Phospholipid scramblase 3

2

0

High-throughput

0.580

High

1277357

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.578

High

950627

KR108
Keratin-associated protein 10-8

1

3

High-throughput

0.573

High

70424

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

848212

MAGA2
Melanoma-associated antigen 2

2

5

High-throughput

0.553

High

1205935

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

19

High-throughput

0.553

High

1385032

ZBT8A
Zinc finger and BTB domain-containing protein 8A

1

0

High-throughput

0.549

High

462571

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

7

High-throughput

0.515

High

384521

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.515

High

386109

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.515

High

767304

MERL
Merlin

1

12

High-throughput

0.515

High

843876

HD
Huntingtin

1

3

High-throughput

0.515

High

1279697

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

1380821

TRI63
E3 ubiquitin-protein ligase TRIM63

1

16

High-throughput

0.494

High

1396238

TRI55
Tripartite motif-containing protein 55

1

18

High-throughput

0.494

High

949966

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.481

High

213997

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

4

Small-scale

0.479

High

378167

TNFA
Tumor necrosis factor

1

2

Small-scale

0.479

High

1045650

TF65
Transcription factor p65

1

9

Small-scale

0.479

High

1141865

EEA1
Early endosome antigen 1

1

9

High-throughput

0.479

High

1396240

LATS2
Serine/threonine-protein kinase LATS2

1

9

Small-scale

0.479

High

876626

NEST
Nestin

1

20

High-throughput

0.470

High

109489

G5E9A7
DM1 locus, WD repeat containing

1

7

High-throughput

0.470

High

517083

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.470

High

1194568

Q4G0R1
PIBF1 protein

1

3

High-throughput

0.470

High

1289874

Q86V38
Atrophin 1

1

5

High-throughput

0.470

High

1369676

KLK6
Kallikrein-6

1

2

High-throughput

0.470

High

562632

RINI
Ribonuclease inhibitor

1

4

High-throughput

0.445

High

718160

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.445

High

730149

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.445

High

765804

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

913561

KIF11
Kinesin-like protein KIF11

1

9

High-throughput

0.445

High

1049667

1433F
14-3-3 protein eta

1

20

High-throughput

0.445

High

1128263

MCM6
DNA replication licensing factor MCM6

1

9

High-throughput

0.445

High

1204782

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

3

High-throughput

0.445

High

1396242

TBK1
Serine/threonine-protein kinase TBK1

1

11

High-throughput

0.445

High

601

NBPFJ
NBPF family member NBPF19

1

6

High-throughput

0.439

High

1361135

PIBF1
Progesterone-induced-blocking factor 1

1

3

High-throughput

0.439

High

880105

AL9A1
4-trimethylaminobutyraldehyde dehydrogenase

1

0

High-throughput

0.426

High

1396243

FBX3
F-box only protein 3

1

0

High-throughput

0.426

High

657657

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.407

High

1323609

LRC47
Leucine-rich repeat-containing protein 47

1

5

High-throughput

0.407

High

1360875

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

11

High-throughput

0.407

High

47398

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

702656

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025