HitPredict

Interactor 1: RARA (P11416)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: Q8BK32 (Q8BK32)
Nuclear receptor corepressor 1
Gene: Ncor1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	7566114
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 462 Mm			1 291
+	Hs
		261381 RARA_HUMAN (1-462): 2.24e-151: 440: 98.27		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		500380 RARB_HUMAN (1-462): 1.43e-152: 443: 78.40		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		488042 RARA_HUMAN (1-462): 2.24e-151: 440: 98.27		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261399 RXRA_HUMAN (1-420): 1.94e-133: 394: 30.16		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261390 RARG_HUMAN (1-443): 4.14e-130: 386: 72.16		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261429 HNF4A_HUMAN (78-462): 1.28e-123: 369: 24.45		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		587211 RXRA_HUMAN (1-420): 1.94e-133: 394: 30.16		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		530817 RARG_HUMAN (1-443): 4.14e-130: 386: 72.16		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261369 ESR1_HUMAN (7-461): 4.97e-118: 359: 22.40		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		261383 THB_HUMAN (50-416): 8.28e-120: 359: 34.61		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		818890 RXRG_HUMAN (1-419): 1.2e-129: 384: 29.76		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261481 PPARA_HUMAN (54-416): 4.26e-116: 350: 28.75		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		782706 HNF4A_HUMAN (78-462): 1.28e-123: 369: 24.45		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		1069095 Q15156_HUMAN (60-462): 3.16e-119: 368: 98.02		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		370824 ESR1_HUMAN (7-461): 4.97e-118: 359: 22.40		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		500510 THB_HUMAN (50-416): 8.28e-120: 359: 34.61		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		261557 ESR2_HUMAN (3-448): 3.28e-107: 329: 24.95		NCOR1_HUMAN (1-290): 3.09e-132: 415: 92.07
+	Hs
		795610 NR4A2_HUMAN (10-417): 3.06e-115: 352: 29.30		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		992457 PPARA_HUMAN (54-416): 4.26e-116: 350: 28.75		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40
+	Hs
		1270043 ESR2_HUMAN (3-448): 3.28e-107: 329: 24.95		NCOR2_HUMAN (1-290): 1.65e-123: 390: 52.40