HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: EPN4 (Q14677)
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)
Gene: CLINT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 625
+	Hs
		601512 FGFR2_HUMAN (1-821): 0: 803: 71.21		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		508299 FGFR1_HUMAN (1-822): 0: 861: 100.00		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		607969 FGFR4_HUMAN (29-808): 0: 664: 55.60		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		872443 EPHA5_HUMAN (3-791): 0: 639: 19.15		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		1057046 EPHA7_HUMAN (3-783): 0: 629: 19.40		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		307502 FGFR1_HUMAN (1-822): 0: 861: 100.00		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		203204 FGFR1_HUMAN (1-822): 0: 861: 100.00		SYNJ1_HUMAN (120-617): 7.92e-35: 143: 10.29
+	Hs
		1057047 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		384843 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		307505 FGFR4_HUMAN (29-808): 0: 664: 55.60		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		307509 EPHA2_HUMAN (3-819): 0: 583: 18.68		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		434196 RET_HUMAN (384-774): 2.63e-98: 332: 45.77		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		385817 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		434323 RET_HUMAN (384-774): 2.63e-98: 332: 45.77		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		384551 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		SC24C_HUMAN (288-606): 1.21e-10: 66.6: 8.96
+	Hs
		729709 VGFR2_HUMAN (43-343): 3.9e-15: 82.1: 16.26		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Mm
		729410 VGFR3_MOUSE (31-128): 2.94e-10: 66.3: 22.12		EPN2_MOUSE (8-555): 6.06e-69: 236: 18.81
+	Hs
		729401 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Bt
		94410 F1MWF1_BOVIN (19-128): 3.11e-09: 62.8: 19.47		F1N579_BOVIN (8-548): 7.3e-68: 233: 22.84
+	Mm
		729409 VGFR3_MOUSE (31-128): 2.94e-10: 66.3: 22.12		EPN1_MOUSE (8-529): 2.71e-64: 223: 24.30