Protein: ATX3L
Ataxin-3-like protein (EC 3.4.19.12) (Machado-Joseph disease protein 1-like)

Gene: ATX3L, ATXN3L
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q9H3M9

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0016579 - protein deubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508615

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

Small-scale

0.710

High

316990

MTA2
Metastasis-associated protein MTA2

2

1

High-throughput

0.601

High

1118778

KLF5
Krueppel-like factor 5

1

1

Small-scale

0.528

High

1362006

RFFL
E3 ubiquitin-protein ligase rififylin

1

4

High-throughput

0.501

High

1380850

TRI63
E3 ubiquitin-protein ligase TRIM63

1

10

High-throughput

0.501

High

1402010

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

3

High-throughput

0.501

High

1419291

TRI55
Tripartite motif-containing protein 55

1

11

High-throughput

0.501

High

601854

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.493

High

123439

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

High-throughput

0.479

High

170348

AURKA
Aurora kinase A

1

3

Small-scale

0.479

High

1102652

MTA1
Metastasis-associated protein MTA1

1

1

High-throughput

0.479

High

1110074

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.479

High

1159002

RBBP7
Histone-binding protein RBBP7

1

3

High-throughput

0.479

High

1368117

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.479

High

1361010

P66B
Transcriptional repressor p66-beta

1

0

High-throughput

0.458

High

1339848

PJA1
E3 ubiquitin-protein ligase Praja-1

1

4

High-throughput

0.457

High

1419219

TRI54
Tripartite motif-containing protein 54

1

10

High-throughput

0.457

High


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Last updated: 11Aug2025