HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27716508, 16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Kelch_1~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 568
+	Hs
		507955 UBC_HUMAN (1-685): 0: 857: 100.00		KEAP1_HUMAN (8-564): 5.21e-156: 461: 35.88
+	Hs
		508729 UBC_HUMAN (1-685): 0: 857: 100.00		KLH28_HUMAN (15-565): 2.02e-154: 456: 37.77
+	Hs
		508257 UBC_HUMAN (1-685): 0: 857: 100.00		KLHL7_HUMAN (19-563): 1.19e-153: 454: 32.13
+	Rn
		1224485 UBC_RAT (1-637): 0: 779: 98.90		KLH17_RAT (11-566): 1.13e-156: 464: 41.04
+	Hs
		508757 UBC_HUMAN (1-685): 0: 857: 100.00		KLH13_HUMAN (380-568): 1.8e-44: 169: 28.06
+	Mm
		509340 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		KEAP1_MOUSE (8-564): 3.8e-156: 462: 35.52
+	Mm
		509181 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		KLHL2_MOUSE (13-567): 3.62e-154: 456: 41.36
+	Mm
		509248 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		KLH28_MOUSE (412-567): 3.87e-30: 126: 31.58