HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 508
+	Hs
		508229 FGFR1_HUMAN (1-822): 0: 861: 100.00		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		203204 FGFR1_HUMAN (1-822): 0: 861: 100.00		SYNJ1_HUMAN (38-463): 1.36e-41: 161: 11.55
+	Hs
		665629 EPHB2_HUMAN (4-819): 0: 640: 18.07		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		508262 FGFR1_HUMAN (1-822): 0: 861: 100.00		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		508233 FGFR1_HUMAN (1-822): 0: 861: 100.00		ITSN2_HUMAN (44-508): 6.18e-18: 89.8: 11.98
+	Hs
		608156 FGFR4_HUMAN (29-808): 0: 664: 55.60		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		508045 FGFR1_HUMAN (1-822): 0: 861: 100.00		SH319_HUMAN (446-503): 2.42e-10: 65.1: 36.21
+	Hs
		508022 FGFR1_HUMAN (1-822): 0: 861: 100.00		ITSN1_HUMAN (399-504): 1.82e-09: 62.5: 20.35
+	Hs
		601605 FGFR2_HUMAN (1-821): 0: 803: 71.21		ITSN2_HUMAN (44-508): 6.18e-18: 89.8: 11.98
+	Mm
		546317 NTRK2_MOUSE (111-762): 1.43e-163: 497: 23.74		ABI1_MOUSE (1-508): 1.42e-122: 369: 91.93
+	Hs
		1081530 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		609289 FGFR3_HUMAN (6-821): 0: 730: 61.22		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		609599 FGFR3_HUMAN (6-821): 0: 730: 61.22		DBNL_HUMAN (316-503): 2.32e-17: 86.1: 20.53
+	Hs
		608185 FGFR4_HUMAN (29-808): 0: 664: 55.60		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		607971 FGFR4_HUMAN (29-808): 0: 664: 55.60		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Hs
		608159 FGFR4_HUMAN (29-808): 0: 664: 55.60		ITSN2_HUMAN (44-508): 6.18e-18: 89.8: 11.98
+	Hs
		608000 FGFR4_HUMAN (29-808): 0: 664: 55.60		SH319_HUMAN (446-503): 2.42e-10: 65.1: 36.21
+	Hs
		607984 FGFR4_HUMAN (29-808): 0: 664: 55.60		ITSN1_HUMAN (399-504): 1.82e-09: 62.5: 20.35
+	Hs
		608026 FGFR4_HUMAN (29-808): 0: 664: 55.60		SH3R1_HUMAN (244-503): 3.15e-09: 61.6: 17.28
+	Hs
		665608 EPHB2_HUMAN (4-819): 0: 640: 18.07		ITSN1_HUMAN (399-504): 1.82e-09: 62.5: 20.35