HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: OTU6B (Q8N6M0)
Deubiquitinase OTUD6B (EC 3.4.19.12) (DUBA-5) (OTU domain-containing protein 6B)
Gene: OTUD6B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.80	0.687

Property	Details
Experiments	29576527, 33141564
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	OTU~ubiquitin
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 293
+	Hs
		508193 UBC_HUMAN (1-685): 0: 857: 100.00		OTU6A_HUMAN (5-285): 1.63e-96: 287: 55.32
+	Hs
		508117 UBC_HUMAN (1-685): 0: 857: 100.00		OTUD1_HUMAN (61-283): 6.34e-43: 155: 18.75
+	Hs
		508106 UBC_HUMAN (1-685): 0: 857: 100.00		OTUD3_HUMAN (92-286): 3.94e-42: 151: 22.00
+	Hs
		507851 UBC_HUMAN (1-685): 0: 857: 100.00		OTUD4_HUMAN (132-286): 2.46e-39: 148: 21.02
+	Hs
		508434 UBC_HUMAN (1-685): 0: 857: 100.00		OTUD5_HUMAN (110-285): 3.54e-39: 146: 20.11
+	Dm
		509788 UBIQP_DROME (1-610): 0: 759: 99.84		OTU_DROME (124-287): 8.59e-38: 143: 17.47
+	Mm
		509057 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		OTUD5_MOUSE (93-285): 8.17e-41: 150: 19.40
+	Mm
		73940 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		OTUD4_MOUSE (133-286): 3.44e-39: 148: 21.80