HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PTN23 (Q9H3S7)
Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14)
Gene: PTPN23

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	26456826, 38803224, 34761192, 40437099
Identification Methods	pull down, proximity labelling technology, cross-linking study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1636
+	Hs
		508336 UBC_HUMAN (1-685): 0: 857: 100.00		PDC6I_HUMAN (9-871): 1.58e-167: 531: 22.21
+	Rn
		1224546 UBC_RAT (1-637): 0: 779: 98.90		PDC6I_RAT (9-872): 7.65e-168: 532: 23.31
+	Hs
		507504 UBC_HUMAN (1-685): 0: 857: 100.00		PTN2_HUMAN (1174-1506): 2.66e-115: 372: 27.55
+	Hs
		987212 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		PTN23_HUMAN (1-1636): 0: 1044: 100.00
+	Hs
		507453 UBC_HUMAN (1-685): 0: 857: 100.00		PTPRF_HUMAN (1203-1453): 1.13e-78: 291: 29.80
+	Sc
		509632 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		BRO1_YEAST (9-793): 2.22e-134: 440: 18.52
+	Sc
		509754 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		PALA_YEAST (9-702): 5.77e-129: 419: 20.20
+	At
		99781 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		BRO1_ARATH (9-834): 4.72e-138: 450: 22.34