HitPredict

Interactor 1: ERR1 (P11474)
Steroid hormone receptor ERR1 (Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1)
Gene: ESRRA

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31907393
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 303
+	Hs
		370707 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		377807 GCR_HUMAN (3-418): 4.49e-103: 324: 28.20		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1269930 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		370425 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		297019 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Hs
		369237 ESR1_HUMAN (5-420): 3.68e-112: 343: 33.86		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		297078 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Hs
		377203 GCR_HUMAN (3-418): 4.49e-103: 324: 28.20		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		213442 GCR_HUMAN (3-418): 4.49e-103: 324: 28.20		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		858657 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		183074 HNF4A_HUMAN (29-418): 1.51e-110: 335: 26.09		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		183050 GCR_HUMAN (3-418): 4.49e-103: 324: 28.20		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		414528 PRGR_HUMAN (71-337): 9.09e-42: 159: 33.46		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		183143 ESR2_HUMAN (4-420): 1.27e-100: 311: 33.11		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		414470 PRGR_HUMAN (71-337): 9.09e-42: 159: 33.46		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		213448 PRGR_HUMAN (71-337): 9.09e-42: 159: 33.46		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71