Protein: LRP1B
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)

Gene: LRP1B
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q9NZR2

Gene Ontology (top 5):
GO:0005041 - low-density lipoprotein particle receptor activity
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0006898 - receptor-mediated endocytosis
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1144678

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

4

High-throughput

0.861

High

720545

AMRP
Alpha-2-macroglobulin receptor-associated protein

2

10

High-throughput

0.811

High

1308077

EGFL6
Epidermal growth factor-like protein 6

2

20

High-throughput

0.811

High

1413921

CRDL1
Chordin-like protein 1

2

20

High-throughput

0.628

High

1355969

NET5
Netrin-5

1

20

High-throughput

0.618

High

1453579

DKK2
Dickkopf-related protein 2

1

9

High-throughput

0.618

High

1160453

TAZ
Tafazzin

3

5

High-throughput

0.609

High

1187865

FX4L6
Forkhead box protein D4-like 6

3

8

High-throughput

0.609

High

1331472

ZFP41
Zinc finger protein 41 homolog

3

20

High-throughput

0.609

High

423343

A4
Amyloid-beta precursor protein

2

14

Small-scale

0.601

High

351735

SG1D1
Secretoglobin family 1D member 1

2

3

High-throughput

0.574

High

1133395

ZN169
Zinc finger protein 169

2

10

High-throughput

0.574

High

1252060

ZN517
Zinc finger protein 517

2

20

High-throughput

0.574

High

1279032

TAFA3
Chemokine-like protein TAFA-3

2

8

High-throughput

0.574

High

1312078

DJC10
DnaJ homolog subfamily C member 10

2

8

High-throughput

0.574

High

1346582

ZN563
Zinc finger protein 563

2

19

High-throughput

0.574

High

1399524

NOE3
Noelin-3

2

2

High-throughput

0.574

High

1437005

ZN408
Zinc finger protein 408

2

20

High-throughput

0.574

High

1447579

ZN331
Zinc finger protein 331

2

20

High-throughput

0.574

High

1453402

ZN224
Zinc finger protein 224

2

8

High-throughput

0.574

High

387753

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

8

Small-scale

0.561

High

882574

ARRB1
Beta-arrestin-1

1

2

High-throughput

0.536

High

1311040

SULF2
Extracellular sulfatase Sulf-2

1

4

High-throughput

0.536

High

535613

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.515

High

851231

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.515

High

1116072

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.494

High

1395302

LCOR
Ligand-dependent corepressor

1

2

High-throughput

0.494

High

49579

FEZF1
Fez family zinc finger protein 1

1

20

High-throughput

0.489

High

351806

LGI1
Leucine-rich glioma-inactivated protein 1

1

7

High-throughput

0.489

High

416652

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

517831

GLI4
Zinc finger protein GLI4

1

20

High-throughput

0.489

High

601984

ZNF8
Zinc finger protein 8

1

20

High-throughput

0.489

High

757361

RNAS4
Ribonuclease 4

1

2

High-throughput

0.489

High

774809

TIMP3
Metalloproteinase inhibitor 3

1

5

High-throughput

0.489

High

1025960

NDP
Norrin

1

2

High-throughput

0.489

High

1105576

OS9
Protein OS-9

1

1

High-throughput

0.489

High

1115468

CUL4B
Cullin-4B

1

13

High-throughput

0.489

High

1181029

DB136
Defensin beta 136

1

1

High-throughput

0.489

High

1181052

DB135
Beta-defensin 135

1

1

High-throughput

0.489

High

1204565

NMS
Neuromedin-S

1

2

High-throughput

0.489

High

1249688

IGFL3
Insulin growth factor-like family member 3

1

8

High-throughput

0.489

High

1252695

ZN574
Zinc finger protein 574

1

10

High-throughput

0.489

High

1324490

AN36B
Ankyrin repeat domain-containing protein 36B

1

12

High-throughput

0.489

High

1329159

DB123
Beta-defensin 123

1

3

High-throughput

0.489

High

1360158

PATE1
Prostate and testis expressed protein 1

1

2

High-throughput

0.489

High

1453582

FBX2
F-box only protein 2

1

10

High-throughput

0.489

High

1453583

CCL26
C-C motif chemokine 26

1

2

High-throughput

0.489

High

1453584

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

20

High-throughput

0.489

High

218881

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.479

High

387909

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

8

Small-scale

0.479

High

388019

FIBG
Fibrinogen gamma chain

1

9

Small-scale

0.479

High

1033276

EWS
RNA-binding protein EWS

1

8

High-throughput

0.479

High

1114494

CUL3
Cullin-3

1

13

High-throughput

0.479

High

1380776

RL36L
Ribosomal protein eL42-like

1

2

High-throughput

0.479

High

1453581

HOOK1
Protein Hook homolog 1

1

8

High-throughput

0.479

High

991113

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

1

High-throughput

0.470

High

405626

HRG
Histidine-rich glycoprotein

1

0

Small-scale

0.458

High

258617

SH21A
SH2 domain-containing protein 1A

1

8

Small-scale

0.437

High

533787

CLUS
Clusterin

1

3

Small-scale

0.437

High

694035

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.437

High

951480

SC61B
Protein transport protein Sec61 subunit beta

1

5

High-throughput

0.437

High

1129941

TTLL4
Tubulin monoglutamylase TTLL4

1

1

High-throughput

0.437

High

1179080

RSPO1
R-spondin-1

1

5

High-throughput

0.437

High

1232383

SFRP4
Secreted frizzled-related protein 4

1

5

High-throughput

0.437

High

1453580

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

1057008

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.417

High

1448506

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.417

High

373346

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.407

High

66815

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

0

High-throughput

0.279

Low

1438550

PROK2
Prokineticin-2

1

0

High-throughput

0.279

Low

74629

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.269

Low

961648

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.249

Low

983996

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.249

Low

1451926

MKS1
Tectonic-like complex member MKS1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025