Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1
Interactor 2: ERF3B (Q8IYD1)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog)
Gene: GSPT2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.974 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10358005, 35044719, 28514442, 33961781, 18447585, 23340509, 14685257 |
| Identification Methods | pull down, two hybrid, unspecified method, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, isothermal titration calorimetry, phage display, surface plasmon resonance |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PABP~PAM2 |
| Common GO terms | GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0003723 - RNA binding GO:0005829 - cytosol |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
