Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA
Interactor 2: RFC1 (P35251)
Replication factor C subunit 1 (Activator 1 140 kDa subunit) (A1 140 kDa subunit) (Activator 1 large subunit) (Activator 1 subunit 1) (DNA-binding protein PO-GA) (Replication factor C 140 kDa subunit) (RF-C 140 kDa subunit) (RFC140) (Replication factor C large subunit)
Gene: RFC1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12192049, 8861969, 8999859, 9092549, 15225546, 26496610, 30301766, 10353443, 12171929, 35271311, 12400013, 9649448, 24958773 |
| Identification Methods | affinity chromatography technology, pull down, far western blotting, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~PCNA_C, AAA~PCNA_N |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
