Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA
Interactor 2: FEN1 (P39748)
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1)
Gene: FEN1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.994 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 26496610, 28514442, 24728180, 29997244, 30184152, 11430825, 26264872, 8876181, 11601988, 33961781, 16216273, 9178907, 22606318, 15616578, 14657243, 12853968, 9545252, 9305916, 32900933 and 13 others
more... |
| Identification Methods | affinity chromatography technology, pull down, fluorescent resonance energy transfer, two hybrid, biochemical, far western blotting, x-ray crystallography, unspecified method, isothermal titration calorimetry, anti tag coimmunoprecipitation and 6 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PCNA_C~XPG_I, PCNA_C~XPG_N, PCNA_N~XPG_N |
| Common GO terms | GO:0000781 - chromosome, telomeric region GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006287 - base-excision repair, gap-filling |
| Homologous interactions | 6 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
