Protein: CYTD
Cystatin-D (Cystatin-5)

Gene: CYTD, CST5
Organism: Homo sapiens
Interactions: 40
UniProt ID: P28325

Gene Ontology (top 5):
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0031982 - vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

485780

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

13

High-throughput

0.691

High

680668

CATS
Cathepsin S

1

13

Small-scale

0.647

High

702400

FKB15
FK506-binding protein 15

2

1

High-throughput

0.549

High

441410

CHLE
Cholinesterase

1

1

High-throughput

0.536

High

449484

CRF
Corticoliberin

1

2

High-throughput

0.536

High

586366

ARSB
Arylsulfatase B

1

4

High-throughput

0.536

High

702388

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.536

High

702389

BTD
Biotinidase

1

1

High-throughput

0.536

High

702391

HSP13
Heat shock 70 kDa protein 13

1

4

High-throughput

0.536

High

702392

RCAN1
Calcipressin-1

1

5

High-throughput

0.536

High

702397

HKDC1
Hexokinase HKDC1

1

1

High-throughput

0.536

High

702401

ARSK
Arylsulfatase K

1

4

High-throughput

0.536

High

702405

VWDE
von Willebrand factor D and EGF domain-containing protein

1

5

High-throughput

0.536

High

702410

GDF15
Growth/differentiation factor 15

1

2

High-throughput

0.536

High

702412

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

3

High-throughput

0.536

High

702387

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.513

High

702402

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.513

High

702404

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

0

High-throughput

0.513

High

702414

IL20
Interleukin-20

1

0

High-throughput

0.513

High

164729

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

1

High-throughput

0.489

High

318632

RHBT1
Rho-related BTB domain-containing protein 1

1

3

High-throughput

0.489

High

479180

HBAT
Hemoglobin subunit theta-1

1

6

High-throughput

0.489

High

702390

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

1

3

High-throughput

0.489

High

702393

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

3

High-throughput

0.489

High

702394

RUXF
Small nuclear ribonucleoprotein F

1

2

High-throughput

0.489

High

702398

PKHG6
Pleckstrin homology domain-containing family G member 6

1

3

High-throughput

0.489

High

702399

MKS3
Meckelin

1

1

High-throughput

0.489

High

702403

ZER1
Protein zer-1 homolog

1

1

High-throughput

0.489

High

702407

FRMD1
FERM domain-containing protein 1

1

3

High-throughput

0.489

High

702408

ZN491
Zinc finger protein 491

1

2

High-throughput

0.489

High

702415

TEN3
Teneurin-3

1

5

High-throughput

0.489

High

702395

IRF8
Interferon regulatory factor 8

1

3

Small-scale

0.479

High

240825

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

702386

GALNS
N-acetylgalactosamine-6-sulfatase

1

4

High-throughput

0.445

High

583819

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

0

High-throughput

0.426

High

702409

HPLN3
Hyaluronan and proteoglycan link protein 3

1

0

High-throughput

0.426

High

702411

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.426

High

702396

NUCG
Endonuclease G, mitochondrial

1

0

High-throughput

0.279

Low

702406

RP25L
Ribonuclease P protein subunit p25-like protein

1

0

High-throughput

0.279

Low

702413

BTBD1
BTB/POZ domain-containing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025