Interactor 1: IMDH2 (P12268)
Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2) (IMPD 2) (IMPDH 2) (EC 1.1.1.205) (Inosine-5'-monophosphate dehydrogenase type II) (IMP dehydrogenase II) (IMPDH-II)
Gene: IMPDH2

Interactor 2: IMDH1 (P20839)
Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I)
Gene: IMPDH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.946

The method score is based on:

Property Details
Experiments 26186194, 28514442, 34079125, 33961781, 32296183, unassigned1304
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBS~CBS, IMPDH~IMPDH
Common GO terms GO:0000166 - nucleotide binding
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003938 - IMP dehydrogenase activity
GO:0005576 - extracellular region
and 8 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 514
Hs

1 514
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Dm
+ Sp
+ Sc
+ Sc
+ Sc
+ Cj
+ Pa
+ Ec
+ Sc

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Last updated: 15 Jul 2024