Protein: RAP2C
Ras-related protein Rap-2c (EC 3.6.5.2)

Gene: RAP2C
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9Y3L5

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

911895

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

5

12

High-throughput

0.924

High

348233

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

4

16

High-throughput

0.892

High

962661

RHOA
Transforming protein RhoA

2

20

High-throughput

0.811

High

518639

RAP2A
Ras-related protein Rap-2a

2

16

High-throughput

0.776

High

921588

PGTB2
Geranylgeranyl transferase type-2 subunit beta

4

3

High-throughput

0.697

High

1086750

RB40B
Ras-related protein Rab-40B

1

20

Small-scale

0.647

High

610955

TCPA
T-complex protein 1 subunit alpha

2

7

High-throughput

0.628

High

821633

TCPZ
T-complex protein 1 subunit zeta

2

7

High-throughput

0.628

High

882229

TCPG
T-complex protein 1 subunit gamma

2

7

High-throughput

0.628

High

899641

TCPD
T-complex protein 1 subunit delta

2

4

High-throughput

0.628

High

1007352

TCPB
T-complex protein 1 subunit beta

2

6

High-throughput

0.628

High

1103677

PHLP
Phosducin-like protein

2

3

High-throughput

0.628

High

1363723

TCPW
T-complex protein 1 subunit zeta-2

2

8

High-throughput

0.628

High

1407644

TCPH
T-complex protein 1 subunit eta

2

6

High-throughput

0.628

High

374299

RASN
GTPase NRas

1

20

High-throughput

0.618

High

375034

RASH
GTPase HRas

1

20

High-throughput

0.618

High

376132

RASK
GTPase KRas

1

20

High-throughput

0.618

High

466537

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

581386

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

953773

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

978422

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

988850

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1434307

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.618

High

1447486

ANLN
Anillin

1

8

High-throughput

0.618

High

1227757

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.575

High

1461065

TNIK
TRAF2 and NCK-interacting protein kinase

1

11

High-throughput

0.575

High

397296

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

391679

FRIH
Ferritin heavy chain

1

2

High-throughput

0.536

High

899294

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.536

High

1459758

LIMA1
LIM domain and actin-binding protein 1

1

16

High-throughput

0.536

High

956124

SPCS3
Signal peptidase complex subunit 3

1

1

High-throughput

0.489

High

458519

ADRB2
Beta-2 adrenergic receptor

1

3

Small-scale

0.481

High

243373

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

414899

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

508881

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

13

Small-scale

0.479

High

883376

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

9

High-throughput

0.479

High

898266

R144A
E3 ubiquitin-protein ligase RNF144A

1

2

Small-scale

0.479

High

942975

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

6

High-throughput

0.479

High

1036017

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.479

High

1117323

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

5

High-throughput

0.479

High

1141090

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1178480

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1197764

MIDN
Midnolin

1

2

High-throughput

0.479

High

1334635

RN149
E3 ubiquitin-protein ligase RNF149

1

14

High-throughput

0.479

High

1419338

TRI55
Tripartite motif-containing protein 55

1

17

High-throughput

0.479

High

1126222

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.458

High

255314

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

564598

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.445

High

848092

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

3

High-throughput

0.445

High

1119387

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1329208

S15A4
Solute carrier family 15 member 4

1

3

High-throughput

0.445

High

1448661

STRN4
Striatin-4

1

4

High-throughput

0.445

High

1449284

S22AB
Solute carrier family 22 member 11

1

2

High-throughput

0.445

High

590106

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.437

High

769591

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

1367666

ESR2
Estrogen receptor beta

1

14

High-throughput

0.437

High

1429413

SPRTN
DNA-dependent metalloprotease SPRTN

1

4

High-throughput

0.437

High

653678

HEMH
Ferrochelatase, mitochondrial

1

3

High-throughput

0.407

High

1007466

S35B1
Solute carrier family 35 member B1

1

1

High-throughput

0.407

High

1340585

MFSD8
Major facilitator superfamily domain-containing protein 8

1

3

High-throughput

0.407

High

1416226

FUND2
FUN14 domain-containing protein 2

1

1

High-throughput

0.407

High

1490679

S35A3
UDP-N-acetylglucosamine transporter

1

1

High-throughput

0.407

High

1417785

SC11C
Signal peptidase complex catalytic subunit SEC11C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025