HitPredict

Interactor 1: FCERA (P12319)
High affinity immunoglobulin epsilon receptor subunit alpha (Fc-epsilon RI-alpha) (FcERI) (IgE Fc receptor subunit alpha)
Gene: FCER1A

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 257 Hs			1 536
+	Hs
		522811 FCG2B_HUMAN (2-247): 4.45e-50: 168: 33.60		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		522812 FCG2C_HUMAN (2-241): 4.57e-49: 166: 34.03		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		412047 FCG2B_HUMAN (2-247): 4.45e-50: 168: 33.60		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		412048 FCG2C_HUMAN (2-241): 4.57e-49: 166: 34.03		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		523211 TUTLB_HUMAN (1-215): 3.83e-24: 103: 13.69		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		433507 TUTLB_HUMAN (1-215): 3.83e-24: 103: 13.69		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		411560 FCG3A_HUMAN (18-241): 3.92e-45: 153: 36.71		LCK_HUMAN (75-534): 0: 552: 58.48
+	Hs
		433610 FCG2B_HUMAN (2-247): 4.45e-50: 168: 33.60		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		433545 FCG2A_HUMAN (19-204): 2.17e-44: 153: 35.48		LYN_HUMAN (1-531): 0: 532: 52.44
+	Dm
		219802 O44924_DROME (2-213): 9.93e-36: 136: 15.23		ABL_DROME (13-536): 3.26e-173: 532: 38.53
+	Mm
		56907 PTPRF_MOUSE (2-141): 1.68e-12: 69: 14.10		FYN_MOUSE (1-536): 0: 597: 68.58
+	Mm
		435878 FCGR1_MOUSE (32-228): 1.2e-23: 100: 21.91		HCK_MOUSE (1-531): 0: 564: 54.51
+	Hs
		442771 FCGR1_HUMAN (32-236): 3.38e-21: 93.2: 20.55		HCK_HUMAN (1-531): 0: 569: 55.22
+	Hs
		434019 ROBO2_HUMAN (7-196): 2.4e-32: 126: 18.14		LYN_HUMAN (1-531): 0: 532: 52.44
+	Dm
		337644 LAR_DROME (30-218): 2.88e-30: 120: 18.27		ABL_DROME (13-536): 3.26e-173: 532: 38.53
+	Hs
		433569 CD22_HUMAN (19-251): 8.05e-29: 116: 18.85		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		434081 TUTLB_HUMAN (1-215): 3.83e-24: 103: 13.69		LYN_HUMAN (1-531): 0: 532: 52.44
+	Mm
		639452 FCRL5_MOUSE (5-243): 1.15e-21: 95.6: 16.80		LYN_MOUSE (1-531): 0: 535: 52.26
+	Hs
		434111 ROBO1_HUMAN (109-255): 2.69e-19: 89: 14.72		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		789014 TUTLB_HUMAN (1-215): 3.83e-24: 103: 13.69		TEC_HUMAN (83-528): 6.43e-155: 458: 37.36