Protein: AF17
Protein AF-17 (ALL1-fused gene from chromosome 17 protein)

Gene: AF17, MLLT6
Organism: Homo sapiens
Interactions: 98
UniProt ID: P55198

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006325 - chromatin organization
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

936503

AF10
Protein AF-10

3

14

Small-scale

0.871

High

936564

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

5

3

Small-scale

0.728

High

936541

CREB5
Cyclic AMP-responsive element-binding protein 5

4

7

High-throughput

0.698

High

921328

CEBPG
CCAAT/enhancer-binding protein gamma

3

10

High-throughput

0.678

High

839872

AF9
Protein AF-9

3

7

Small-scale

0.675

High

186521

TRI18
E3 ubiquitin-protein ligase Midline-1

2

5

High-throughput

0.628

High

429593

JUN
Transcription factor Jun

2

9

High-throughput

0.628

High

583510

ATF2
Cyclic AMP-dependent transcription factor ATF-2

2

5

High-throughput

0.628

High

605066

JUND
Transcription factor JunD

2

5

High-throughput

0.628

High

605247

ATF7
Cyclic AMP-dependent transcription factor ATF-7

2

5

High-throughput

0.628

High

714807

EF1D
Elongation factor 1-delta

2

4

High-throughput

0.628

High

936551

EEA1
Early endosome antigen 1

2

3

High-throughput

0.628

High

936545

TLE5
TLE family member 5

2

3

High-throughput

0.606

High

936568

ZC3HA
Zinc finger CCCH domain-containing protein 10

2

0

High-throughput

0.602

High

936576

UBQL4
Ubiquilin-4

1

3

High-throughput

0.582

High

936548

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

0

High-throughput

0.580

High

936567

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.580

High

161601

RGPD8
RANBP2-like and GRIP domain-containing protein 8

2

5

High-throughput

0.574

High

451356

NFM
Neurofilament medium polypeptide

2

4

High-throughput

0.574

High

665408

EF1B
Elongation factor 1-beta

2

4

High-throughput

0.574

High

687769

SYVC
Valine--tRNA ligase

2

1

High-throughput

0.574

High

936544

EF1A2
Elongation factor 1-alpha 2

2

2

High-throughput

0.574

High

936560

GCC2
GRIP and coiled-coil domain-containing protein 2

2

6

High-throughput

0.574

High

936542

ENL
Protein ENL

2

10

Small-scale

0.558

High

936555

GRAP1
GRIP1-associated protein 1

2

2

High-throughput

0.553

High

168660

CSKP
Peripheral plasma membrane protein CASK

1

1

High-throughput

0.541

High

936569

MED15
Mediator of RNA polymerase II transcription subunit 15

1

4

High-throughput

0.541

High

340309

YETS4
YEATS domain-containing protein 4

1

7

High-throughput

0.536

High

635574

FILA
Filaggrin

1

3

High-throughput

0.536

High

687941

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.536

High

693620

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

848465

MAGA8
Melanoma-associated antigen 8

1

4

High-throughput

0.536

High

936538

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.536

High

936549

CUL3
Cullin-3

1

1

High-throughput

0.536

High

936579

DAXX
Death domain-associated protein 6

1

2

High-throughput

0.536

High

936553

CEBPE
CCAAT/enhancer-binding protein epsilon

1

7

Small-scale

0.527

High

936581

UBQL1
Ubiquilin-1

1

2

High-throughput

0.523

High

936535

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.515

High

85474

B7ZLY0
PHC2 protein

1

7

High-throughput

0.515

High

421795

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

936585

NEMO
NF-kappa-B essential modulator

1

5

High-throughput

0.501

High

936537

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

1

High-throughput

0.494

High

140827

NOP56
Nucleolar protein 56

1

1

High-throughput

0.489

High

801241

HSPA9
Stress-70 protein, mitochondrial

1

2

High-throughput

0.489

High

936571

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

4

High-throughput

0.489

High

936584

TACC3
Transforming acidic coiled-coil-containing protein 3

1

4

High-throughput

0.489

High

182016

ZBT22
Zinc finger and BTB domain-containing protein 22

1

6

High-throughput

0.481

High

209975

CRX
Cone-rod homeobox protein

1

2

High-throughput

0.481

High

221104

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.481

High

587036

ITF2
Transcription factor 4

1

7

High-throughput

0.481

High

893775

MEOX2
Homeobox protein MOX-2

1

7

High-throughput

0.481

High

936561

PHC2
Polyhomeotic-like protein 2

1

7

High-throughput

0.481

High

936570

HTF4
Transcription factor 12

1

7

High-throughput

0.481

High

936572

NSD3
Histone-lysine N-methyltransferase NSD3

1

10

High-throughput

0.481

High

142914

NFIB
Nuclear factor 1 B-type

1

10

High-throughput

0.479

High

473883

NFIC
Nuclear factor 1 C-type

1

13

High-throughput

0.479

High

487136

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

588314

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

685139

PAX6
Paired box protein Pax-6

1

1

High-throughput

0.479

High

775816

HNF1B
Hepatocyte nuclear factor 1-beta

1

4

High-throughput

0.479

High

789455

PPARG
Peroxisome proliferator-activated receptor gamma

1

12

High-throughput

0.479

High

799820

COIL
Coilin

1

3

High-throughput

0.479

High

883491

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

886679

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

919836

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.479

High

936539

H31
Histone H3.1

1

20

High-throughput

0.479

High

936540

H33
Histone H3.3

1

20

High-throughput

0.479

High

936543

TLE3
Transducin-like enhancer protein 3

1

8

High-throughput

0.479

High

936547

NFIA
Nuclear factor 1 A-type

1

13

High-throughput

0.479

High

936550

NFIX
Nuclear factor 1 X-type

1

13

High-throughput

0.479

High

936552

TRIP4
Activating signal cointegrator 1

1

1

High-throughput

0.479

High

936559

ZN793
Zinc finger protein 793

1

2

High-throughput

0.479

High

936562

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

936565

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

936566

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

936573

FOXQ1
Forkhead box protein Q1

1

1

High-throughput

0.479

High

936580

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

936582

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

936583

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

519354

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

662547

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

High-throughput

0.458

High

839728

EPS15
Epidermal growth factor receptor substrate 15

1

4

High-throughput

0.457

High

936536

KR108
Keratin-associated protein 10-8

1

2

High-throughput

0.439

High

936554

ENOX2
Ecto-NOX disulfide-thiol exchanger 2

1

1

High-throughput

0.439

High

936574

CEP44
Centrosomal protein of 44 kDa

1

1

High-throughput

0.439

High

767803

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

936277

AFAD
Afadin

1

7

High-throughput

0.437

High

936546

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.437

High

936563

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.437

High

936556

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

884583

SYCC
Cysteine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.328

High

936557

SGO1
Shugoshin 1

2

0

High-throughput

0.328

High

936558

IQEC1
IQ motif and SEC7 domain-containing protein 1

2

0

High-throughput

0.328

High

936578

GULP1
PTB domain-containing engulfment adapter protein 1

2

0

High-throughput

0.328

High

936577

ATX10
Ataxin-10

1

0

High-throughput

0.268

Low

105651

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

475547

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

936575

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025