Interactor 1: LOX5 (P12527)
Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34)
Gene: Alox5

Interactor 2: AL5AP (P20291)
Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)
Gene: Alox5ap

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.40 0.60 0.494

The method score is based on:

Property Details
Experiments 19075240
Identification Methods fluorescence microscopy, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002540 - leukotriene production involved in inflammatory response
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0019370 - leukotriene biosynthetic process
GO:0019372 - lipoxygenase pathway
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 673
Rn

1 161
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024