HitPredict

Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	9442085
Identification Methods	two hybrid, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 769 Hs			1 317
+	Hs
		403852 ITB1_HUMAN (5-766): 0: 703: 44.61		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		574522 ITB5_HUMAN (23-760): 0: 635: 37.52		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Hs
		929713 TEN1_HUMAN (613-712): 6.79e-10: 65.1: 17.65		RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00
+	Dm
		247276 TENM_DROME (613-720): 2.96e-11: 69.7: 13.49		FBXW7_DROME (3-128): 9.64e-20: 92: 19.53