HitPredict

Interactor 1: TCPA (P12612)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha)
Gene: TCP1

Interactor 2: PP11 (P20604)
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)
Gene: SIT4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.50	0.593

Property	Details
Experiments	37968396, 20489023, 19536198
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Sc			1 311
+	Hs
		826603 TCPG_HUMAN (4-555): 0: 575: 29.53		PP2AB_HUMAN (2-311): 0: 520: 57.10
+	Hs
		826610 TCPG_HUMAN (4-555): 0: 575: 29.53		PP2AA_HUMAN (1-311): 0: 519: 56.59
+	Hs
		573203 TCPA_HUMAN (9-556): 0: 569: 62.23		PP2AB_HUMAN (2-311): 0: 520: 57.10
+	Hs
		826591 TCPG_HUMAN (4-555): 0: 575: 29.53		PP4C_HUMAN (4-311): 0: 514: 60.39
+	Hs
		573211 TCPA_HUMAN (9-556): 0: 569: 62.23		PP2AA_HUMAN (1-311): 0: 519: 56.59
+	Hs
		573192 TCPA_HUMAN (9-556): 0: 569: 62.23		PP4C_HUMAN (4-311): 0: 514: 60.39
+	Sc
		519896 TCPA_YEAST (1-559): 0: 589: 100.00		PP2A1_YEAST (6-311): 1.72e-175: 491: 54.58
+	Hs
		915267 TCPH_HUMAN (4-556): 0: 555: 31.78		PP2AB_HUMAN (2-311): 0: 520: 57.10
+	Hs
		930969 TCPH_HUMAN (4-556): 0: 555: 31.78		PP2AA_HUMAN (1-311): 0: 519: 56.59
+	Hs
		890997 TCPH_HUMAN (4-556): 0: 555: 31.78		PP4C_HUMAN (4-311): 0: 514: 60.39
+	Hs
		821154 TCPE_HUMAN (17-552): 0: 530: 29.31		PP2AB_HUMAN (2-311): 0: 520: 57.10
+	Hs
		821143 TCPE_HUMAN (17-552): 0: 530: 29.31		PP4C_HUMAN (4-311): 0: 514: 60.39
+	Sc
		594322 TCPG_YEAST (7-552): 0: 537: 28.75		PP11_YEAST (1-311): 0: 506: 100.00
+	Sc
		594334 TCPH_YEAST (1-555): 0: 531: 31.00		PP11_YEAST (1-311): 0: 506: 100.00
+	Sc
		618772 TCPG_YEAST (7-552): 0: 537: 28.75		PP2A1_YEAST (6-311): 1.72e-175: 491: 54.58
+	Sc
		618781 TCPH_YEAST (1-555): 0: 531: 31.00		PP2A1_YEAST (6-311): 1.72e-175: 491: 54.58
+	Hs
		135401 TCPG_HUMAN (4-555): 0: 575: 29.53		PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39
+	Hs
		135360 TCPA_HUMAN (9-556): 0: 569: 62.23		PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39
+	Hs
		135491 TCPH_HUMAN (4-556): 0: 555: 31.78		PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39
+	Hs
		135397 TCPE_HUMAN (17-552): 0: 530: 29.31		PPP6_HUMAN (7-292): 3.77e-148: 419: 65.39