Interactor 1: BMP2 (P12643)
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
Gene: BMP2
Interactor 2: AVR2B (Q13705)
Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)
Gene: ACVR2B
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.58 | 1.00 | 0.768 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Activin_recp~TGF_beta |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0006355 - regulation of DNA-templated transcription GO:0007507 - heart development GO:0030501 - positive regulation of bone mineralization GO:0030509 - BMP signaling pathway and 2 others more... |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024