Protein: TGIF1
Homeobox protein TGIF1 (5'-TG-3'-interacting factor 1)

Gene: TGIF1
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q15583

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1103185

CTBP1
C-terminal-binding protein 1

4

1

Small-scale

0.713

High

941442

CTBP2
C-terminal-binding protein 2

4

1

High-throughput

0.712

High

1014520

SMAD3
Mothers against decapentaplegic homolog 3

3

11

Small-scale

0.656

High

714144

PML
Protein PML

2

1

Small-scale

0.641

High

1109754

HDAC1
Histone deacetylase 1

3

7

Small-scale

0.640

High

1150370

SMAD2
Mothers against decapentaplegic homolog 2

2

11

Small-scale

0.620

High

1150377

MDFI
MyoD family inhibitor

2

0

High-throughput

0.613

High

422148

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.611

High

1150378

TGIF2
Homeobox protein TGIF2

1

20

High-throughput

0.575

High

1150376

SIN3A
Paired amphipathic helix protein Sin3a

1

8

Small-scale

0.573

High

429946

JUN
Transcription factor Jun

1

3

Small-scale

0.561

High

1150385

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

291797

STK16
Serine/threonine-protein kinase 16

1

2

High-throughput

0.515

High

520077

ANDR
Androgen receptor

1

8

Small-scale

0.501

High

640353

DRD1
D(1A) dopamine receptor

1

1

Small-scale

0.501

High

181115

AXIN1
Axin-1

1

1

Small-scale

0.500

High

996167

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.494

High

1150381

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.493

High

154530

PLPP1
Phospholipid phosphatase 1

1

0

High-throughput

0.493

High

361796

PNPH
Purine nucleoside phosphorylase

1

0

High-throughput

0.493

High

919984

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.493

High

1056746

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.493

High

1150384

AXIN2
Axin-2

1

1

Small-scale

0.481

High

288091

FOXH1
Forkhead box protein H1

1

15

Small-scale

0.479

High

833580

SOX3
Transcription factor SOX-3

1

9

Small-scale

0.479

High

886886

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

1150371

SMAD1
Mothers against decapentaplegic homolog 1

1

11

Small-scale

0.479

High

1150374

ESR2
Estrogen receptor beta

1

8

High-throughput

0.479

High

1150372

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

1150380

MKKS
Molecular chaperone MKKS

1

0

High-throughput

0.458

High

1150373

RIF1
Telomere-associated protein RIF1

1

2

High-throughput

0.457

High

1150382

COMD3
COMM domain-containing protein 3

1

0

High-throughput

0.279

Low

127336

LEG8
Galectin-8

1

0

Small-scale

0.276

Low

699763

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.268

Low

1150383

VPS29
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.268

Low

369675

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.265

Low

1150375

MOB3A
MOB kinase activator 3A

1

0

High-throughput

0.251

Low

1150379

Q9HB66
Alternative protein MKKS

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025