Protein: MISP
Mitotic interactor and substrate of PLK1 (Mitotic spindle positioning protein)

Gene: MISP
Organism: Homo sapiens
Interactions: 163
UniProt ID: Q8IVT2

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0005884 - actin filament
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

547127

EZRI
Ezrin

4

5

High-throughput

0.698

High

1217910

ANLN
Anillin

4

0

High-throughput

0.664

High

719745

RADI
Radixin

2

5

High-throughput

0.628

High

1191980

RABEK
Rab9 effector protein with kelch motifs

2

2

High-throughput

0.628

High

1217906

E41L1
Band 4.1-like protein 1

2

4

High-throughput

0.628

High

1217925

E41L3
Band 4.1-like protein 3

2

3

High-throughput

0.628

High

995017

GOGA2
Golgin subfamily A member 2

2

2

High-throughput

0.606

High

1050700

FHL2
Four and a half LIM domains protein 2

2

2

High-throughput

0.606

High

1076457

TRIP6
Thyroid receptor-interacting protein 6

2

2

High-throughput

0.606

High

1077018

MARE1
Microtubule-associated protein RP/EB family member 1

2

0

Small-scale

0.585

High

146685

SOCS7
Suppressor of cytokine signaling 7

2

0

High-throughput

0.580

High

204378

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

641470

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

869681

TERF1
Telomeric repeat-binding factor 1

2

0

High-throughput

0.580

High

901698

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.580

High

904027

HNRPK
Heterogeneous nuclear ribonucleoprotein K

2

0

High-throughput

0.580

High

1020785

TRAF2
TNF receptor-associated factor 2

2

0

High-throughput

0.580

High

1217884

TRIB3
Tribbles homolog 3

2

0

High-throughput

0.580

High

1217887

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

2

0

High-throughput

0.580

High

1217902

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.580

High

299267

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

2

4

High-throughput

0.574

High

850678

KS6A3
Ribosomal protein S6 kinase alpha-3

2

2

High-throughput

0.574

High

1071657

KS6A2
Ribosomal protein S6 kinase alpha-2

2

2

High-throughput

0.574

High

1073446

KS6A1
Ribosomal protein S6 kinase alpha-1

2

2

High-throughput

0.574

High

1217891

KLDC3
Kelch domain-containing protein 3

2

3

High-throughput

0.574

High

1217927

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

2

1

High-throughput

0.574

High

983634

FAK1
Focal adhesion kinase 1

1

1

Small-scale

0.561

High

638338

RBTN2
Rhombotin-2

2

2

High-throughput

0.553

High

638533

RBTN1
Rhombotin-1

2

2

High-throughput

0.553

High

1080872

HSPB2
Heat shock protein beta-2

2

1

High-throughput

0.553

High

1136584

FHL5
Four and a half LIM domains protein 5

2

2

High-throughput

0.553

High

1217876

PIHD2
PIH1 domain-containing protein 2

2

1

High-throughput

0.553

High

1217896

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

1

High-throughput

0.553

High

1217914

PIHD1
PIH1 domain-containing protein 1

2

1

High-throughput

0.553

High

1217920

HSPB8
Heat shock protein beta-8

2

1

High-throughput

0.553

High

117753

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.536

High

640126

MOES
Moesin

1

5

High-throughput

0.536

High

885650

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

1

High-throughput

0.536

High

906523

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

High-throughput

0.536

High

1217877

MY18A
Unconventional myosin-XVIIIa

1

2

High-throughput

0.536

High

1217883

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.536

High

1217912

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.536

High

835867

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.515

High

62154

RCCD1
RCC1 domain-containing protein 1

1

0

High-throughput

0.513

High

161682

GAK
Cyclin-G-associated kinase

1

0

High-throughput

0.513

High

217659

EFNA2
Ephrin-A2

1

0

High-throughput

0.513

High

245712

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

382609

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

0

High-throughput

0.513

High

427607

ANXA2
Annexin A2

1

0

High-throughput

0.513

High

428291

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

448950

CD48
CD48 antigen

1

0

High-throughput

0.513

High

598213

FLNA
Filamin-A

1

0

High-throughput

0.513

High

724910

MYH9
Myosin-9

1

0

High-throughput

0.513

High

789638

I12R1
Interleukin-12 receptor subunit beta-1

1

0

High-throughput

0.513

High

809353

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.513

High

813095

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

881528

ARL4C
ADP-ribosylation factor-like protein 4C

1

0

High-throughput

0.513

High

896929

ARP2
Actin-related protein 2

1

0

High-throughput

0.513

High

969602

CENPE
Centromere-associated protein E

1

0

High-throughput

0.513

High

1072539

EPHA7
Ephrin type-A receptor 7

1

0

High-throughput

0.513

High

1084994

DREB
Drebrin

1

0

High-throughput

0.513

High

1217869

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

1217909

CAN10
Calpain-10

1

0

High-throughput

0.513

High

1217911

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.513

High

1217918

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

1217926

GPR55
G-protein coupled receptor 55

1

0

High-throughput

0.513

High

1217928

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

1217915

KLH14
Kelch-like protein 14

1

1

High-throughput

0.489

High

1217919

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.489

High

414983

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

210114

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

737905

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

High-throughput

0.479

High

835439

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.479

High

841260

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

969833

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1051351

DCTN1
Dynactin subunit 1

1

1

Small-scale

0.479

High

1217879

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

1217899

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

High-throughput

0.479

High

1217905

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

1217917

TES
Testin

1

3

High-throughput

0.479

High

232927

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

529380

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

1066356

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1085311

FSCN1
Fascin

1

0

High-throughput

0.458

High

1191043

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

1217885

RANB9
Ran-binding protein 9

1

0

High-throughput

0.458

High

1217908

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

308863

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

1063928

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.437

High

1217895

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.437

High

787266

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.426

High

968180

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

1081226

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

High-throughput

0.426

High

1217874

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.426

High

255905

OBSL1
Obscurin-like protein 1

2

0

High-throughput

0.328

High

570636

DCAM
S-adenosylmethionine decarboxylase proenzyme

2

0

High-throughput

0.328

High

253082

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

888582

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

1039672

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.316

High

1115448

SPAS1
Spermatogenesis-associated serine-rich protein 1

2

0

High-throughput

0.316

High

1124825

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1127554

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1138807

IKBP1
Interleukin-1 receptor-associated kinase 1-binding protein 1

2

0

High-throughput

0.316

High

1139594

MORN5
MORN repeat-containing protein 5

2

0

High-throughput

0.316

High

1154439

PRR5L
Proline-rich protein 5-like

2

0

High-throughput

0.316

High

1156455

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.316

High

1156919

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

2

0

High-throughput

0.316

High

1161270

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.316

High

1161639

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.316

High

1169329

ZN620
Zinc finger protein 620

2

0

High-throughput

0.316

High

1183735

DPPA4
Developmental pluripotency-associated protein 4

2

0

High-throughput

0.316

High

1217870

RIBC1
RIB43A-like with coiled-coils protein 1

2

0

High-throughput

0.316

High

1217875

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

1217886

CRBN
Protein cereblon

2

0

High-throughput

0.316

High

1217888

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.316

High

1217892

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

2

0

High-throughput

0.316

High

1217894

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.316

High

1217900

SPC1L
Speriolin-like protein

2

0

High-throughput

0.316

High

1217903

GO45
Golgin-45

2

0

High-throughput

0.316

High

1217921

IKZF3
Zinc finger protein Aiolos

2

0

High-throughput

0.316

High

1217922

PNMA2
Paraneoplastic antigen Ma2

2

0

High-throughput

0.316

High

1046096

DX39B
Spliceosome RNA helicase DDX39B

2

0

Small-scale

0.305

High

1024814

DUS4
Dual specificity protein phosphatase 4

2

0

High-throughput

0.298

High

200405

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.279

Low

277331

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

331662

B3GT4
Beta-1,3-galactosyltransferase 4

1

0

High-throughput

0.279

Low

851147

PRELP
Prolargin

1

0

High-throughput

0.279

Low

968867

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1108760

INAVA
Innate immunity activator protein

1

0

High-throughput

0.279

Low

1125788

VWA2
von Willebrand factor A domain-containing protein 2

1

0

High-throughput

0.279

Low

1154452

FSTL4
Follistatin-related protein 4

1

0

High-throughput

0.279

Low

1217867

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

1217868

ZDH23
Palmitoyltransferase ZDHHC23

1

0

High-throughput

0.279

Low

1217871

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1217880

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1217881

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

1217882

T3HPD
Trans-3-hydroxy-L-proline dehydratase

1

0

High-throughput

0.279

Low

1217889

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.279

Low

1217890

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low

1217898

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

1217904

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

1217907

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.279

Low

1217913

KLHL1
Kelch-like protein 1

1

0

High-throughput

0.279

Low

1217923

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

1073691

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.268

Low

1157015

ZN774
Zinc finger protein 774

1

0

High-throughput

0.268

Low

1217873

BOLL
Protein boule-like

1

0

High-throughput

0.268

Low

1217872

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low

149022

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

1217901

TOLIP
Toll-interacting protein

1

0

High-throughput

0.249

Low

1217916

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.249

Low

1217924

FBW1A
F-box/WD repeat-containing protein 1A

1

0

High-throughput

0.249

Low

233534

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

398027

ISG15
Ubiquitin-like protein ISG15

1

0

High-throughput

0.249

Low

917548

H4
Histone H4

1

0

High-throughput

0.249

Low

941128

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

Small-scale

0.249

Low

961188

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low

1126643

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.249

Low

1170697

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1217878

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.249

Low

1217893

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.249

Low

1217897

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.249

Low

1153278

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024