HitPredict

Interactor 1: HLAC (P10321)
HLA class I histocompatibility antigen, C alpha chain (HLA-C) (HLA-Cw) (Human leukocyte antigen C)
Gene: HLA-C

Interactor 2: SIA8D (Q92187)
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV)
Gene: ST8SIA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005794 - Golgi apparatus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 366 Hs			1 359
+	Hs
		719729 HLAF_HUMAN (4-349): 2e-141: 406: 77.75		SIA8D_HUMAN (1-359): 2.57e-155: 442: 100.00
+	Hs
		1362519 HMR1_HUMAN (8-349): 6.45e-111: 328: 36.92		SIA8D_HUMAN (1-359): 2.57e-155: 442: 100.00
+	Hs
		209374 HLAF_HUMAN (4-349): 2e-141: 406: 77.75		SIA8C_HUMAN (64-356): 9.96e-105: 314: 39.26
+	Hs
		191433 HLAF_HUMAN (4-349): 2e-141: 406: 77.75		SIA8E_HUMAN (70-356): 6.2e-102: 307: 33.33
+	Hs
		379859 HLAB_HUMAN (1-363): 1.8e-155: 442: 85.95		SIAT1_HUMAN (54-344): 2.49e-66: 216: 18.81
+	Hs
		719711 HLAF_HUMAN (4-349): 2e-141: 406: 77.75		SIAT6_HUMAN (90-349): 5.69e-80: 250: 20.15
+	Hs
		520736 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		SIAT1_HUMAN (54-344): 2.49e-66: 216: 18.81
+	Hs
		520928 HLAC_HUMAN (1-366): 7.07e-154: 439: 100.00		SIA7C_HUMAN (104-350): 1.95e-66: 213: 19.77
+	Hs
		191458 HMR1_HUMAN (8-349): 6.45e-111: 328: 36.92		SIA8E_HUMAN (70-356): 6.2e-102: 307: 33.33