Protein: HMR1
Major histocompatibility complex class I-related protein 1 (MHC class I-related protein 1) (Class I histocompatibility antigen-like protein)

Gene: HMR1, MR1
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q95460

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002474 - antigen processing and presentation of peptide antigen via MHC class I
GO:0002854 - positive regulation of T cell mediated cytotoxicity directed against tumor cell target
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

568078

HLAE
HLA class I histocompatibility antigen, alpha chain E

3

16

High-throughput

0.861

High

1286855

TM11B
Transmembrane protease serine 11B

2

12

High-throughput

0.811

High

520954

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

16

High-throughput

0.789

High

705981

CD1B
T-cell surface glycoprotein CD1b

2

17

High-throughput

0.789

High

1249583

BTNL8
Butyrophilin-like protein 8

2

6

High-throughput

0.789

High

963531

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

17

Small-scale

0.716

High

231057

VEGFD
Vascular endothelial growth factor D

1

1

High-throughput

0.691

High

438904

CD1A
T-cell surface glycoprotein CD1a

1

17

High-throughput

0.691

High

567943

PRG2
Bone marrow proteoglycan

1

11

High-throughput

0.691

High

607403

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

16

High-throughput

0.691

High

688605

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

20

High-throughput

0.691

High

688677

NKG2C
NKG2-C type II integral membrane protein

1

20

High-throughput

0.691

High

1180947

HFE
Hereditary hemochromatosis protein

1

17

High-throughput

0.691

High

1186224

CEA21
Cell adhesion molecule CEACAM21

1

6

High-throughput

0.691

High

1306880

INLR1
Interferon lambda receptor 1

1

2

High-throughput

0.691

High

1363119

CLC2B
C-type lectin domain family 2 member B

1

20

High-throughput

0.691

High

1376967

BTNL2
Butyrophilin-like protein 2

1

7

High-throughput

0.691

High

1376969

CAH14
Carbonic anhydrase 14

1

2

High-throughput

0.691

High

1376970

CLC4E
C-type lectin domain family 4 member E

1

13

High-throughput

0.691

High

1376973

ST14
Suppressor of tumorigenicity 14 protein

1

12

High-throughput

0.691

High

1192271

ZACN
Ligand-gated cation channel ZACN

3

5

High-throughput

0.667

High

1376963

CC50A
Cell cycle control protein 50A

3

5

High-throughput

0.667

High

1376956

FATE1
Fetal and adult testis-expressed transcript protein

3

0

High-throughput

0.646

High

1332611

I17RC
Interleukin-17 receptor C

2

1

High-throughput

0.628

High

1362519

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

13

High-throughput

0.628

High

1143766

PON2
Serum paraoxonase/arylesterase 2

2

2

High-throughput

0.611

High

341462

CDS2
Phosphatidate cytidylyltransferase 2

2

1

High-throughput

0.606

High

1275385

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

4

High-throughput

0.606

High

1325353

GLT15
Polypeptide N-acetylgalactosaminyltransferase 15

2

5

High-throughput

0.606

High

932747

EMP3
Epithelial membrane protein 3

2

0

High-throughput

0.580

High

1059088

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.580

High

1376964

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

380113

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

15

High-throughput

0.575

High

380571

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

20

High-throughput

0.575

High

1376959

TECT2
Tectonic-2

2

4

High-throughput

0.574

High

191458

SIA8E
Alpha-2,8-sialyltransferase 8E

1

13

High-throughput

0.536

High

341344

ECEL1
Endothelin-converting enzyme-like 1

1

5

High-throughput

0.536

High

548085

PSPC
Surfactant protein C

1

5

High-throughput

0.536

High

880051

DNSL1
Deoxyribonuclease-1-like 1

1

3

High-throughput

0.536

High

914870

NDST2
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

1

2

High-throughput

0.536

High

1245901

BRID5
BRICHOS domain-containing protein 5

1

5

High-throughput

0.536

High

1308277

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

1

High-throughput

0.536

High

1376957

T106A
Transmembrane protein 106A

1

6

High-throughput

0.536

High

1376958

ASIC4
Acid-sensing ion channel 4

1

9

High-throughput

0.536

High

1376960

CST11
Cystatin-11

1

1

High-throughput

0.536

High

1376962

UD17
UDP-glucuronosyltransferase 1A7

1

6

High-throughput

0.536

High

1376965

DNJB9
DnaJ homolog subfamily B member 9

1

6

High-throughput

0.536

High

1376968

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

15

High-throughput

0.536

High

1376971

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

1

High-throughput

0.536

High

342638

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

337184

APOM
Apolipoprotein M

1

2

High-throughput

0.489

High

647392

IDS
Iduronate 2-sulfatase

1

1

High-throughput

0.489

High

1293633

DYR2
Dihydrofolate reductase 2, mitochondrial

1

2

High-throughput

0.489

High

218586

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

1376961

SIAE
Sialate O-acetylesterase

1

1

High-throughput

0.479

High

1376972

ITM2B
Integral membrane protein 2B

1

5

High-throughput

0.479

High

1376974

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

1376966

XPO7
Exportin-7

1

3

High-throughput

0.437

High

1198736

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

1206271

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025