HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25468996
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008013 - beta-catenin binding GO:0045296 - cadherin binding GO:0070062 - extracellular exosome GO:0072659 - protein localization to plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 337
+	Hs
		153864 CADH1_HUMAN (1-882): 0: 836: 100.00		NHRF1_HUMAN (2-337): 3.61e-70: 224: 48.87
+	Hs
		521992 CADH1_HUMAN (1-882): 0: 836: 100.00		MAGI3_HUMAN (14-296): 6.63e-18: 86.9: 18.15
+	Hs
		522143 CADH1_HUMAN (1-882): 0: 836: 100.00		MAGI1_HUMAN (2-204): 1.44e-16: 83.1: 21.95
+	Hs
		521900 CADH1_HUMAN (1-882): 0: 836: 100.00		DLG1_HUMAN (87-235): 1.55e-13: 73.5: 17.31
+	Hs
		522077 CADH1_HUMAN (1-882): 0: 836: 100.00		INADL_HUMAN (3-129): 2.49e-13: 73: 21.81
+	Hs
		521928 CADH1_HUMAN (1-882): 0: 836: 100.00		SCRIB_HUMAN (4-185): 3.63e-13: 72.7: 18.37
+	Hs
		1377991 PCDBC_HUMAN (430-867): 8.01e-71: 251: 15.54		USH1C_HUMAN (142-310): 4.02e-13: 71.9: 14.54