HitPredict

Interactor 1: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1

Interactor 2: RHG35 (Q9NRY4)
Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A)
Gene: ARHGAP35

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 9034330, 35271311, 8419471, 8189062
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras, Ras~RasGAP
Common GO terms GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008360 - regulation of cell shape
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1047
Hs

1 1499
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Last updated: 15 Jul 2024