HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: PTPRA (P18433)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48)
Gene: PTPRA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 23532252, 11923305, 33961781, 10698938
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Y_phosphatase, SH2~Y_phosphatase
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0070062 - extracellular exosome
GO:0097060 - synaptic membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 536
Hs

1 802
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024