HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: ANR54 (Q6NXT1)
Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein)
Gene: ANKRD54

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 300
+	Hs
		433389 YES_HUMAN (1-536): 0: 604: 73.85		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		411697 LCK_HUMAN (75-534): 0: 552: 58.48		ANK3_HUMAN (83-297): 6.75e-61: 211: 20.31
+	Hs
		411885 LCK_HUMAN (75-534): 0: 552: 58.48		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Mm
		639458 LYN_MOUSE (1-531): 0: 535: 52.26		ANR54_MOUSE (1-300): 4.51e-70: 220: 92.00
+	Hs
		433832 LYN_HUMAN (1-531): 0: 532: 52.44		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		433730 LYN_HUMAN (1-531): 0: 532: 52.44		ANK3_HUMAN (83-297): 6.75e-61: 211: 20.31
+	Hs
		433701 LYN_HUMAN (1-531): 0: 532: 52.44		ANK2_HUMAN (82-297): 7.44e-60: 208: 19.62
+	Hs
		434071 LYN_HUMAN (1-531): 0: 532: 52.44		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Hs
		846484 BLK_HUMAN (45-531): 1.62e-179: 516: 57.58		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Mm
		976833 ITK_MOUSE (46-525): 3.08e-160: 471: 33.74		ANR54_MOUSE (1-300): 4.51e-70: 220: 92.00
+	Hs
		434072 LYN_HUMAN (1-531): 0: 532: 52.44		ANR50_HUMAN (124-297): 4.84e-39: 148: 21.17
+	Hs
		788998 TEC_HUMAN (83-528): 6.43e-155: 458: 37.36		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		986383 BTK_HUMAN (43-527): 1.18e-154: 458: 34.35		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		337406 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		DAPK1_HUMAN (103-298): 1.54e-38: 146: 19.19
+	Dm
		337696 SRC64_DROME (56-535): 7.2e-178: 514: 51.43		TNKS_DROME (24-295): 3.24e-30: 121: 15.83