Protein: CG12
G1/S-specific cyclin CLN2

Gene: CG12, CLN2
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P20438

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0000321 - re-entry into mitotic cell cycle after pheromone arrest
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

364322

CDK1
Cyclin-dependent kinase 1

26

20

Small-scale

0.992

High

632438

STE20
Serine/threonine-protein kinase STE20

5

12

Small-scale

0.906

High

632407

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

10

3

Small-scale

0.755

High

632403

FAR1
Cyclin-dependent kinase inhibitor FAR1

6

5

Small-scale

0.736

High

632401

CKS1
Cyclin-dependent kinases regulatory subunit

6

20

Small-scale

0.733

High

632415

CGS6
S-phase entry cyclin-6

1

7

High-throughput

0.691

High

632423

RGA1
Rho-type GTPase-activating protein 1

3

1

Small-scale

0.656

High

632431

SKP1
Suppressor of kinetochore protein 1

3

6

Small-scale

0.650

High

632414

STE5
Protein STE5

3

3

Small-scale

0.640

High

632435

CIP1
Cyclin-dependent kinase inhibitor CIP1

3

2

Small-scale

0.640

High

560585

KIN1
Serine/threonine protein kinase KIN1

1

3

High-throughput

0.621

High

632429

RIM15
Serine/threonine-protein kinase RIM15

1

10

Small-scale

0.618

High

632425

HSP7E
Heat shock protein SSC3, mitochondrial

2

1

High-throughput

0.601

High

632443

CDC53
Cell division control protein 53

2

10

Small-scale

0.601

High

632416

BUD2
Inhibitory regulator protein BUD2/CLA2

2

2

High-throughput

0.590

High

460711

CDC4
Cell division control protein 4

2

11

Small-scale

0.584

High

632422

SIC1
Protein SIC1

2

6

Small-scale

0.584

High

632433

CDH1
APC/C activator protein CDH1

2

20

Small-scale

0.584

High

632440

TUS1
Rho1 guanine nucleotide exchange factor TUS1

2

1

Small-scale

0.584

High

525897

HSP72
Heat shock protein SSA2

2

15

High-throughput

0.571

High

632413

BEM3
GTPase-activating protein BEM3

2

1

Small-scale

0.563

High

632420

SRL3
Protein SRL3

2

0

Small-scale

0.559

High

632444

WHI5
G1-specific transcriptional repressor WHI5

2

0

Small-scale

0.559

High

632426

SSB2
Ribosome-associated molecular chaperone SSB2

2

18

High-throughput

0.552

High

632412

MLF3
Protein MLF3

1

0

High-throughput

0.513

High

632436

DIG1
Down-regulator of invasive growth 1

1

1

Small-scale

0.508

High

632437

DIG2
Down-regulator of invasive growth 2

1

1

Small-scale

0.508

High

574770

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

4

Small-scale

0.501

High

632424

MBO1
Gamma tubulin complex adapter SPC72

1

1

Small-scale

0.501

High

416858

CDC25
Cell division control protein 25

1

1

Small-scale

0.479

High

509388

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

632402

ACE2
Metallothionein expression activator

1

7

Small-scale

0.479

High

632405

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

9

Small-scale

0.479

High

632409

CDC48
Cell division control protein 48

1

2

Small-scale

0.479

High

632410

2AAA
Protein phosphatase PP2A regulatory subunit A

1

1

Small-scale

0.479

High

632418

BMH2
Protein BMH2

1

4

Small-scale

0.479

High

632419

WHI3
Protein WHI3

1

1

Small-scale

0.479

High

632432

MSN5
Protein MSN5

1

5

Small-scale

0.479

High

632434

2ABA
Protein phosphatase PP2A regulatory subunit B

1

1

Small-scale

0.479

High

632439

IMB1
Importin subunit beta-1

1

2

Small-scale

0.479

High

632442

ACM1
APC/C-CDH1 modulator 1

1

1

Small-scale

0.479

High

632406

SSD1
Protein SSD1

1

0

Small-scale

0.460

High

632404

SIN3
Transcriptional regulatory protein SIN3

1

0

Small-scale

0.458

High

632428

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

523028

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

543785

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

632411

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

632417

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

632408

BUD3
Bud site selection protein 3

1

1

Small-scale

0.437

High

632430

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

632421

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

632441

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.279

Low

585527

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

632427

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025